Pregled bibliografske jedinice broj: 1065260
The effect of magnesium alloy WE43 structure caused by equal channel angular pressing on the mechanical properties and the cytotoxicity to tumor cells in vitro
The effect of magnesium alloy WE43 structure caused by equal channel angular pressing on the mechanical properties and the cytotoxicity to tumor cells in vitro // Book of abstracts of the 14th International Symposium of Croatian Metallurgical Society - SHMD '2020, Materials and metallurgy (tiskano u: Metalurgija 59 (2020) 3) / Mamuzić, Ilija (ur.).
Zagreb: Hrvatsko metalurško društvo, 2020. str. 438-438 (poster, međunarodna recenzija, sažetak, znanstveni)
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Naslov
The effect of magnesium alloy WE43 structure caused by equal channel angular pressing on the mechanical properties
and the cytotoxicity to tumor cells in vitro
(The effect of magnesium alloy WE43 structure
caused by equal channel angular pressing on the
mechanical properties and the cytotoxicity to
tumor cells in vitro)
Autori
Martynenko, N. ; Anisimova, N. ; Kiselevskiy, M. ; Temralieva, D. ; Tokar, A. ; Raab, G. ; Dobatkin, S. ; Estrin, Yu. ; Mamuzić, Ilija
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Book of abstracts of the 14th International Symposium of Croatian Metallurgical Society - SHMD '2020, Materials and metallurgy (tiskano u: Metalurgija 59 (2020) 3)
/ Mamuzić, Ilija - Zagreb : Hrvatsko metalurško društvo, 2020, 438-438
Skup
14th International Symposium of Croatian Metallurgical Society "Materials and Metallurgy" (SHMD ‘2020)
Mjesto i datum
Šibenik, Hrvatska, 21.06.2020. - 26.06.2020
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
magnesium alloy ; tumor cells ; in vitro
Sažetak
In this study, a degradable magnesium alloy WE43 was subjected to equal channel angular pressing (ECAP). Grain refi nement down to 0.7 – 1 μm and a transformation of texture induced by ECAP were shown to lead to increased the ultimate tensile strength (up to 300 MPa) combined with enhanced ductility (13.2%). The data presented show that co-incubation of tumor LNCaP and MDA-MB-231 cells with the WE43 alloy led to a decrease of their viability and proliferation. It was established that ECAP led to enhancement of the alloy cytotoxic activity against tumor cells. This study demonstrated that alloy WE43 can be considered as a promising candidate for application in orthopedic implants in clinical oncology.
Izvorni jezik
Engleski
Znanstvena područja
Metalurgija
Napomena
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