Naslov
Nutraceuticals and Metastasis Development

Autori
Saftić Martinović, Lara ; Peršurić, Željka ; Pavelić, Krešimir

Izvornik
Molecules (1420-3049) 25 (2020), 9; 2222, 14

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
nutrigenomics ; metastases ; small molecules ; antioxidants ; high-fat diet ; phytoestrogens

Sažetak
Nutrigenomics is a discipline that studies the effects of various dietary components on gene expression and molecular mechanisms via “omics” technologies. Many studies are focused on revealing the pathways of the anticancer properties of various nutraceuticals. However, it has been shown that metastasis, a multifactorial disease that develops from primary tumors in cascades, is responsible for almost 90% of cancer deaths. Regrettably, the effects of consumption of different nutraceuticals on metastasis development have not yet been sufficiently explored. A few studies on the subject have revealed the promotional effects of some nutraceuticals on metastasis development. Additionally, it has been shown that certain compounds can have beneficial effects on reduction of the primary tumor, but afterwards promote the spread of metastases. Therefore, in this review we discuss results published in the past five years focused on the effects of different nutraceuticals on metastasis development.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Nutricionizam, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

POVEZANOST RADA