Naslov
Diels-Alder Reaction (Part 1)
(Editorial (Thematic Issue: Diels-Alder Reaction (Part 1)))

Autori
Markovic, Dean ; Porée, François-Hugues

Izvornik
Current Organic Chemistry (1385-2728) 20 (2016), 21; 2135-2135

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, uvodnik, znanstveni

Ključne riječi
Diels-Alder reaction, inverse electron demand, hetero-Diels-Alder, Diels-Alder click chemistry, metal-promoted Diels-Alder reaction, artificial enzymecatalyzed Diels-Alder

Sažetak
Since its first disclosure in 1928, the Diels-Alder reaction has emerged as a highly powerful tool in the chemist’s arsenal. The versatility of these [4+2]-cycloadditions led to applications in many different areas of organic chemistry including natural product total and semi synthesis, medicinal chemistry or macromolecular chemistry. Besides, the mechanistic understanding at the molecular level of stereo and electronic effects has allowed the drastic improvements of old and development of many novel versions of these reactions. For example, the intramolecular variations, the hetero-Diels-Alder reactions, the catalytic, the metal-assisted and/or the asymmetric versions, among others, have been developed. Despite all the work conducted in this field, the Diels-Alder cycloadditions still remain an inexhaustible spring of new applications and a stimulating topic of the modern organic chemistry research. This Special Issue features mainly the last decade developments on Diels-Alder reactions.Eleven independent accounts highlighting a different aspect of these reactions are proposed and are divided in two separate parts.

Izvorni jezik
Engleski

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