Pregled bibliografske jedinice broj: 1058846
Vitamin D Deficiency and Inflammation Activity in Crohn`s Disease at the Time of Diagnosis
Vitamin D Deficiency and Inflammation Activity in Crohn`s Disease at the Time of Diagnosis // The Firest Mediterranean Symposium on Vitamnin D / Drustvo za osteoporozu u Federaciji Bosne i Hercegovine (ur.).
Sarajevo: Drustvo za osteoporozu u Federaciji Bosne i Hercegovine, 2019. str. 1-1 (predavanje, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 1058846 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Vitamin D Deficiency and Inflammation Activity in
Crohn`s Disease at the Time of Diagnosis
Autori
Rajkovaca I, Miskic B, Cosic V, Vcev A, Mihaljevic S
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
The Firest Mediterranean Symposium on Vitamnin D
/ Drustvo za osteoporozu u Federaciji Bosne i Hercegovine - Sarajevo : Drustvo za osteoporozu u Federaciji Bosne i Hercegovine, 2019, 1-1
Skup
The First Mediterranean Symposium on Vitamin D
Mjesto i datum
Sarajevo, Bosna i Hercegovina, 22.03.2019. - 24.03.2019
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
vitamin D, deficiency, inflamation, bowel, chron, disease
Sažetak
Background: Vitamin D deficiency is often found in patients with IBD. Vitamin D has immunomodulatory activity avoiding excessive immune response and has the function of repairing the intestinal mucosal barrier in IBD. Patients and Methods: We have analyzed 20 patients with Crohn`s disease at the time of diagnosis. Patients received vitamin D supplementation with their standard therapy – corticosteroids and/or azathioprine .We measured vitamin D levels, sedimentation rate, CRP and calprotectin levels at the time of diagnosis and compared them to CDAI score. Results:There was 12 male and 8 female patients, average age of 34.12 +-. 60% of patients had vitamin D deficiency and 20% had vitamin D insufficiency. The mean CDAI was 286.12 +- 58.22. There was a correlation between CDAI and vitamin D deficiency (p= 0.63, p<0.05, Spearman rank correlation).Also we found correlation between calprotectin levels and vitamin D deficiency (p=0.50, p<0.05, Spearman rank correlation).Vitamin D levels are unrelated to sedimentation rate and CRP. Conclusion: Our study confirmed previous results about vitamin D deficiency and insufficiency being prevelent in IBD. Also, vitamin D defficiency is associated with higher calprotectin levels and CDAI suggesting its potential antiinflammatory role in intestinal tissue.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Ustanove:
Fakultet za dentalnu medicinu i zdravstvo, Osijek
