Naslov
Pheochromocytoma:a case report

Autori
Marušić, Romana ; Turk, Tajana ; Degmečić, Dunja ; Bačun, Tatjana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Skup
International Translational Medicine Congress of Students and Young Physicians

Mjesto i datum
Osijek, Hrvatska, 13.02.2020. - 14.02.2020

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
adrenal tumor ; pheochromocytoma ; arterial hypertension ; palpitation ; tachycardia

Sažetak
Introduction:Pheochromocytoma is a tumor arising from chromaffin cells of the adrenal gland medulla and sympathetic ganglia that releases catecholamines. Case report: The clinical photograph shows a 62-year-old patient having arterial hypertension, type 2 diabetes, and hypercholesterolemia, who had a reduced appetite for three months, lost 10 kg, suffered from pain in the lumbosacral spine and felt depressed. The abdominal ultrasound showed an inhomogeneous tumor mass on the right adrenal gland, 5cm x 4.5 cm in size, with minor cystic spaces in the middle. The computed tomography (CT) scan of the abdomen showed a sharply defined heterogenous mass on the right adrenal gland of 4.2x5 cm in diameter with higher absorption coefficients on the edge and lower in the middle (central necrosis), measuring a density of 26 Hounsfield units (HU), on native non-homogeneous post-contrast opacification sections, showing a slow flush of the contrast on post-contrast sections (a relative wash out amounting to 9%, and the absolute one accounting for 20%) a pheochromocytoma is clinically suspected. Medical records indicate that during the previous four years the patient occasionally suffered from palpitation and supraventricular tachycardia with blood pressure levels up to 190/100mmHg. The laboratory analysis showed elevated plasma levels of metanephrine and normetanephrine (12 and 9 times), confirming the diagnosis. A pre- opeartive preparation was performed using alpha-adrenergic receptor blockers (phenoxybenzamine), followed by beta blockers (bisoprolol). Following the surgery, the histopathological examination confirmed the pheochromocytoma diagnosis. The metanephrine and normetanephrine follow-up results were normal. Annual follow-up checkup is recommended for the next 10 years. Conclusion: In case of a clinically suspected pheochromocytoma or during the adrenal gland incidentaloma CT imaging the adenoma is excluded (including a density of more than 10 HU), a biochemical analysis of pheochromocytoma must be performed.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA