Marine Natural Products with High Anticancer Activities

Matulja, Dario; Wittine, Karlo; Malatesti, Nela; Laclef, Sylvain; Turks, Maris; Markovic, Maria Kolympadi; Ambrožić, Gabriela; Marković, Dean

doi:10.2174/0929867327666200113154115

Pregled bibliografske jedinice broj: 1056042

Marine Natural Products with High Anticancer Activities

Matulja, Dario; Wittine, Karlo; Malatesti, Nela; Laclef, Sylvain; Turks, Maris; Markovic, Maria Kolympadi; Ambrožić, Gabriela; Marković, Dean

Marine Natural Products with High Anticancer Activities // Current medicinal chemistry, 27 (2020), 8; 1243-1307 doi:10.2174/0929867327666200113154115 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 1056042 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Marine Natural Products with High Anticancer Activities

Autori
Matulja, Dario ; Wittine, Karlo ; Malatesti, Nela ; Laclef, Sylvain ; Turks, Maris ; Markovic, Maria Kolympadi ; Ambrožić, Gabriela ; Marković, Dean

Izvornik
Current medicinal chemistry (0929-8673) 27 (2020), 8; 1243-1307

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Anticancer ; antitumor ; cytotoxic ; marine ; medicinal chemistry ; natural products

Sažetak
This review covers recent literature from 2012- 2019 concerning 170 marine natural products and their semisynthetic analogues with strong anticancer biological activities. Reports that shed light on cellular and molecular mechanisms and biological functions of these compounds, thus advancing the understanding in cancer biology are also included. Biosynthetic studies and total syntheses, which have provided access to derivatives and have contributed to the proper structure or stereochemistry elucidation or revision are mentioned. The natural compounds isolated from marine organisms are divided into nine groups, namely: alkaloids, sterols and steroids, glycosides, terpenes and terpenoids, macrolides, polypeptides, quinones, phenols and polyphenols, and miscellaneous products. An emphasis is placed on several drugs originating from marine natural products that have already been marketed or are currently in clinical trials.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Interdisciplinarne prirodne znanosti, Interdisciplinarne biotehničke znanosti, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

POVEZANOST RADA

Projekti:
IP-2016-06-3568 - Preparation of Porous Thin-film Materials for water Purification using Atomic Layer Deposition (ALD) (WATPUR) (Ambrožić, Gabriela, HRZZ - 2016-06) ( CroRIS)
EK-KF-KK.01.1.1.01.0002 - Bioprospecting Jadranskog mora (Jerković, Igor; Dragović-Uzelac, Verica; Šantek, Božidar; Čož-Rakovac, Rozelinda; Kraljević Pavelić, Sandra; Jokić, Stela, EK ) ( CroRIS)
EK-EFRR-RC.2.2.06-0001 - Razvoj istraživačke infrastrukture na kampusu Sveučilišta u Rijeci (RISK) (Ožanić, Nevenka, EK - Operativni program Regionalna konkurentnost) ( CroRIS)
NadSve-Sveučilište u Rijeci-uniri-prirod-18-102 - Razvoj novih nanotehnološki unaprijeđenih materijala otpornih na stvaranje bakterijskih biofilmova (Marković, Dean, NadSve ) ( CroRIS)
IP-2019-04-8846 - In-silico potpomognut dizajn supstrata za hvatanje CO2 u katalitičkoj formaciji karbonata i karbamata (INDICATIOR) (Marković, Dean, HRZZ - 2019-04) ( CroRIS)
UNIRI-biomed-18-133 (1277)