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Pregled bibliografske jedinice broj: 1054420

The shape of titanium dioxide nanomaterials modulates their protection efficacy against ultraviolet light in human skin cells


Ilić, Krunoslav; Selmani, Atiđa; Milić, Mirta; Matijević Glavan, Tanja; Zapletal, Emilija; Ćurlin, Marija; Yokosawa, Tadahiro; Vinković Vrček, Ivana; Pavičić, Ivan
The shape of titanium dioxide nanomaterials modulates their protection efficacy against ultraviolet light in human skin cells // Journal of nanoparticle research, 22 (2020), 71, 13 doi:10.1007/s11051-020-04791-0 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1054420 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
The shape of titanium dioxide nanomaterials modulates their protection efficacy against ultraviolet light in human skin cells

Autori
Ilić, Krunoslav ; Selmani, Atiđa ; Milić, Mirta ; Matijević Glavan, Tanja ; Zapletal, Emilija ; Ćurlin, Marija ; Yokosawa, Tadahiro ; Vinković Vrček, Ivana ; Pavičić, Ivan

Izvornik
Journal of nanoparticle research (1388-0764) 22 (2020); 71, 13

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
UVB radiation ; Skin ; TiO2NM ; Genotoxicity ; Inflammatory response ; Viability ; Health effects

Sažetak
Skin protection against ultraviolet (UV) radiation is necessary to reduce sunburn damage (erythema) and has been recognized as an important preventive measure against the development of cancer. Many sun-blocking pharmaceutical products are based on titanium dioxide nanomaterials (TiO2 NMs) due to their UV barrier properties. This study aimed to assess if the UV protective efficiency of TiO2 NMs depends on their shape. We prepared TiO2 nanowires (TNW), TiO2 nanotubes (TNT), and TiO2 nanoplates (TNP) and tested their effects on human keratinocytes before and after UVB irradiation under in vitro exposure settings. The UVB radiation was applied at the dose equivalent to the UV component observed in one medial erythemal dose. The biological effects of TiO2 NMs on nonirradiated and UVB-irradiated keratinocytes were observed by means of cell viability, genotoxicity, and inflammatory response. The obtained results clearly showed that the effects of TiO2 NMs in vitro, either cytotoxic or protective, depend on their shape. These observations highlight the beneficial properties of nanomaterials that can improve the quality and efficacy of nano-enabled products only if the safe-by-design concept has been implemented during the innovation process.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija, Farmacija



POVEZANOST RADA


Projekti:
HRZZ-IP-2016-06-2436 - Značaj interakcija metalnih nanočestica sa sumpornim biomolekulama za nano-bio sučelje (NanoFaceS) (Vinković Vrček, Ivana, HRZZ - 2016-06) ( CroRIS)

Ustanove:
Institut za medicinska istraživanja i medicinu rada, Zagreb,
Institut "Ruđer Bošković", Zagreb,
Medicinski fakultet, Zagreb

Poveznice na cjeloviti tekst rada:

doi link.springer.com

Citiraj ovu publikaciju:

Ilić, Krunoslav; Selmani, Atiđa; Milić, Mirta; Matijević Glavan, Tanja; Zapletal, Emilija; Ćurlin, Marija; Yokosawa, Tadahiro; Vinković Vrček, Ivana; Pavičić, Ivan
The shape of titanium dioxide nanomaterials modulates their protection efficacy against ultraviolet light in human skin cells // Journal of nanoparticle research, 22 (2020), 71, 13 doi:10.1007/s11051-020-04791-0 (međunarodna recenzija, članak, znanstveni)
Ilić, K., Selmani, A., Milić, M., Matijević Glavan, T., Zapletal, E., Ćurlin, M., Yokosawa, T., Vinković Vrček, I. & Pavičić, I. (2020) The shape of titanium dioxide nanomaterials modulates their protection efficacy against ultraviolet light in human skin cells. Journal of nanoparticle research, 22, 71, 13 doi:10.1007/s11051-020-04791-0.
@article{article, author = {Ili\'{c}, Krunoslav and Selmani, Ati\dja and Mili\'{c}, Mirta and Matijevi\'{c} Glavan, Tanja and Zapletal, Emilija and \'{C}urlin, Marija and Yokosawa, Tadahiro and Vinkovi\'{c} Vr\v{c}ek, Ivana and Pavi\v{c}i\'{c}, Ivan}, year = {2020}, pages = {13}, DOI = {10.1007/s11051-020-04791-0}, chapter = {71}, keywords = {UVB radiation, Skin, TiO2NM, Genotoxicity, Inflammatory response, Viability, Health effects}, journal = {Journal of nanoparticle research}, doi = {10.1007/s11051-020-04791-0}, volume = {22}, issn = {1388-0764}, title = {The shape of titanium dioxide nanomaterials modulates their protection efficacy against ultraviolet light in human skin cells}, keyword = {UVB radiation, Skin, TiO2NM, Genotoxicity, Inflammatory response, Viability, Health effects}, chapternumber = {71} }
@article{article, author = {Ili\'{c}, Krunoslav and Selmani, Ati\dja and Mili\'{c}, Mirta and Matijevi\'{c} Glavan, Tanja and Zapletal, Emilija and \'{C}urlin, Marija and Yokosawa, Tadahiro and Vinkovi\'{c} Vr\v{c}ek, Ivana and Pavi\v{c}i\'{c}, Ivan}, year = {2020}, pages = {13}, DOI = {10.1007/s11051-020-04791-0}, chapter = {71}, keywords = {UVB radiation, Skin, TiO2NM, Genotoxicity, Inflammatory response, Viability, Health effects}, journal = {Journal of nanoparticle research}, doi = {10.1007/s11051-020-04791-0}, volume = {22}, issn = {1388-0764}, title = {The shape of titanium dioxide nanomaterials modulates their protection efficacy against ultraviolet light in human skin cells}, keyword = {UVB radiation, Skin, TiO2NM, Genotoxicity, Inflammatory response, Viability, Health effects}, chapternumber = {71} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


Citati:





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