Naslov
Stability of Isothiocyanates in Conditions Mimicking Hydrodistillation and Microwave- Assisted Distillation

Autori
Đulović, Azra ; Popović, Marijana ; Burčul, Franko ; Blažević, Ivica

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
Knjiga sažetaka - 26 HRVATSKI SKUP KEMIČARA I KEMIJSKIH INŽENJERA / Galić, Nives ; Rogošić, Marko - Zagreb : Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI), 2019, 68-68

ISBN
978-953-6894-67-3

Skup
26. hrvatski skup kemičara i kemijskih inženjera (26HSKIKI) ; 4. simpozij Vladimir Prelog

Mjesto i datum
Šibenik, Hrvatska, 09.04.2019. - 12.04.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
isothiocyanates, hydrodistillation, microwave-assisted distillation, stability

Sažetak
Glucosinolates are thioglucosidic metabolites occurring mainly in the order Brassicales.[1] They represent natural precursors of isothiocyanates (ITCs), small molecules that contain a very electrophilic carbon atom and readily react with various nucleophiles such as hydroxy, amino, or thiol group, forming O- thiocarbamates, thiourea derivatives, or dithiocarbamates, respectively.[2] Degradation products induced by thermal treatment of ITCs are especially important because they have potential to contribute to wide range of properties, with an emphasis on the impact on biological activity. A selection of two ITCs (allyl ITC as aliphatic and benzyl ITC as arylaliphatic) were subjected to stability testing. The major objective was mimicking standard hydrodistillation and microwave- assisted distillation conditions for 1 h. The same samples in an aqueous solution were heated and refluxed at 100 °C for 1 h. After distillation processes, volatile fractions were analyzed using GC-MS, as well as the volatiles resulting from liquid−liquid extraction of aqueous phases using dichloromethane. The present experiments indicated that ITCs were generally stable in case of hydro- and microwave distillation conditions. On the other hand, decomposition of ITCs in solution under the reflux resulted in thiourea as the major degradation compound.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA