Naslov
Herbalife associated severe hepatotoxicity in a previously healthy women

Autori
Jurčić, Dragan ; Gabrić, Maruška ; Troskot Perić, Rosana ; Liberati Pršo, Ana Marija ; Mirat, Jure ; Včev, Aleksandar ; Alerić, Ivan ; Ebling, Barbara

Izvornik
Acta clinica Croatica (0353-9466) 58 (2019), 4; 771-776

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Herbalife ; Plant preparations ; Dietary supplements ; Liver failure

Sažetak
Lately there has been an increased consumption of herbal preparations, distributed as nutritional supplements, often claimed to be natural and harmless. However, as their use is not subjected to strict pre-marketing testing and regulations, their ingredients are not clearly defined and there is no quality control or proof of their effectiveness and safety. A growing body of references accentuate their harmful effects, in particular hepatotoxicity, which varies from minimal hepatogram cnahges to fulminant hepatitis requiring liver transplantation. This case report describes liver damage that was highly suspected to originate from Herbalife products consumption. We excluded alcohol, viral, metabolic, autoimmune and neoplastic causes of liver lesions, as well as vascular disease, but we noticed a connection between the use of Herbalife products and liver damage. The exact mechanism of liver damage in our patient was not determined. After removing the Herbalife products, liver damage resolved and there was no need to perform liver biopsy. Taking into consideration the growing consumption of herbal products and their potential harmfulness, we consider that more strict regulations of their production process and sale are necessary, including exact identification of active substances with a list of ingredients, toxicologic testing and obligatory side effect report.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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