Pregled bibliografske jedinice broj: 1050338
Cas3 protein - a review of a multi-tasking machine
Cas3 protein - a review of a multi-tasking machine // Genes, 11 (2020), 208; 1-14 doi:10.3390/genes11020208 (međunarodna recenzija, pregledni rad, znanstveni)
CROSBI ID: 1050338 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Cas3 protein - a review of a multi-tasking machine
Autori
Liu, He ; James, Michael St. John ; Radovcic, Marin ; Ivancic-Bace, Ivana ; Bolt, Edward L.
Izvornik
Genes (2073-4425) 11
(2020), 208;
1-14
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni
Ključne riječi
CRISPR ; Cas3 ; helicase ; nuclease ; biofilm
Sažetak
Cas3 has essential functions in CRISPR immunity but its other activities and roles, in vitro and in cells, are less widely known. We offer a concise review of the latest understanding and the questions arising from studies of Cas3 mechanism during CRISPR immunity, and highlight recent attempts at using Cas3 for genetic editing. We then spotlight involvement of Cas3 in other aspects of cell biology, for which understanding is lacking - these focus on CRISPR systems as regulators of cellular processes in addition to defense against mobile genetic elements.
Izvorni jezik
Engleski
Znanstvena područja
Biologija
Napomena
HRZZ projekt
POVEZANOST RADA
Projekti:
HRZZ-IP-2016-06-8861 - Cas3 kao kontrolna točka obrane CRISPR-Cas: razjašnjenje njegove regulacije istraživanjem stabilnosti proteina i prepisivanja u bakteriji Escherichia coli (Cas3 status) (Ivančić Baće, Ivana, HRZZ - 2016-06) ( CroRIS)
Ustanove:
Prirodoslovno-matematički fakultet, Zagreb
Poveznice na cjeloviti tekst rada:
Pristup cjelovitom tekstu rada doi www.mdpi.com www.mdpi.com doi.orgCitiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE