Arterial stiffness in patients with coronary artery disease: relation with in-stent restenosis following percutaneous coronary intervention

Prskalo, Zrinko; Brizic, Ivica; Markota, Darko; Markota, Ivica; Boban, Mladen; Tomic, Monika; Starcevic, Boris

doi:10.1186/s12872-016-0305-4

Pregled bibliografske jedinice broj: 1049635

Arterial stiffness in patients with coronary artery disease: relation with in-stent restenosis following percutaneous coronary intervention

Prskalo, Zrinko; Brizic, Ivica; Markota, Darko; Markota, Ivica; Boban, Mladen; Tomic, Monika; Starcevic, Boris

Arterial stiffness in patients with coronary artery disease: relation with in-stent restenosis following percutaneous coronary intervention // BMC Cardiovascular Disorders, 16 (2016), 128, 6 doi:10.1186/s12872-016-0305-4 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 1049635 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Arterial stiffness in patients with coronary artery disease: relation with in-stent restenosis following percutaneous coronary intervention

Autori
Prskalo, Zrinko ; Brizic, Ivica ; Markota, Darko ; Markota, Ivica ; Boban, Mladen ; Tomic, Monika ; Starcevic, Boris

Izvornik
BMC Cardiovascular Disorders (1471-2261) 16 (2016); 128, 6

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Vascular stiffness ; Coronary artery disease ; Coronary restenosis

Sažetak
Background: Coronary artery disease (CAD) is one of the most important issues in modern medicine due to its high mortality and prevalence. An early detection and prevention can reduce morbidity and mortality. Arterial stiffness is a potent and independent predictor of CAD. We aimed to investigate the arterial stiffness in CAD patients undergoing the coronary angiography. Also, we investigated a possible correlation between arterial stiffness and in-stent restenosis (ISR), an important limitation of percutaneous coronary intervention (PCI). Methods: The study included 160 patients undergoing coronary angiography, treated either with PCI or with CABG. The pulse wave velocity (PWV) and augmentation index (AIx) were measured by the Arteriograph. Results: PWV in the CAD group (12.24 +/- 2.78 m/s) was significantly higher compared to the control group (8.27 +/- 1.89 m/s). PWV in ISR and left main (LM) stenosis group (14.03 +/- 3.15 and 13.89 +/- 2.95 m/s) was significantly higher compared to the control and CAD groups. Peripheral and central AIx were significantly higher in CAD group (1.38 +/- 30. 63 % and 38.35 +/- 15.52 %) than in control group (-11.35 +/- 26.74 % and 26.91 +/- 10.62 %). Patients with LM stenosis have significantly higher values of peripheral and central AIx (23.37 +/- 23.77 % and 49.71 +/- 12.02 %) than the CAD and ISR group. Conclusions: The study confirmed a positive correlation between arterial stiffness measures, PWV and AIx, and CAD. Also, this study showed the correlation between PWV and ISR which can help to select more appropriate stent.

Izvorni jezik
Engleski

POVEZANOST RADA

Profili:

Mladen Boban (autor)