Naslov
Present and Future in Personalized Clinical and Laboratory Approaches to In Vitro Fertilization Procedures

Autori
Radojčić Badovinac, Anđelka ; Smiljan Severinski, Neda ; Dević Pavlić, Sanja

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, znanstveni

Knjiga
Personalized Medicine in Healthcare Systems. Europeanization and Globalization

Urednik/ci
Bodiroga-Vukobrat, Nada ; Rukavina, Daniel ; Pavelić, Krešimir ; Sander, Gerald

Izdavač
Springer

Grad
Cham

Godina
2019

Raspon stranica
99-105

ISBN
978-3-030-16465-2

ISSN
2366-0953

Ključne riječi
In Vitro Fertilization, Personalized Medicine

Sažetak
Personalized approach to a patient engaged into an infertility treatment has been present since the early beginnings of the assisted reproductive technologies, and is constantly developing because of the progress of therapy, medication and laboratory methods. Personalization of the infertility treatment can be discussed on three different levels: approach to the patient, selection of gametes and assessment of embryos. Personalization of the approach to the patient includes adjustment of controlled ovarian stimulation strategy as well as usage of the biomarkers for the ovarian response to the hormone stimulation. Regarding gametes and embryo assessment, personalization includes application of novel OMICS and other high-throughput methods for selection of the oocytes and/or embryos with the highest developmental potential. Personalization of the treatment approaches and ovarian stimulation protocols along with improved laboratory techniques would lead to better treatment efficiency with improved safety for the patient, higher percentage of babies born per cycle and higher cumulative live birth rate for couple in shorter period of time.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

POVEZANOST RADA