Naslov
Towards a light activated molecular transporter

Autori
Nicoli, Federico ; Groppi, Jessica ; Tranfić Bakić, Marina ; Curcio, Massimiliano ; Corrà, Stefano ; Baroncini, Massimo ; Silvi, Serena ; Credi, Alberto

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
Book of abstracts / - , 2020, P28-P28

Skup
European-Winter School on Physical Organic Chemistry 2020 (E-WISPOC20)

Mjesto i datum
Bressanone, Italija, 02.02.2020. - 07.02.2020

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
molecular machines ; light ; directional motion ; self-assembly
(molekulski strojevi ; svjetlost ; usmjereno gibanje ; samoudruživanje)

Sažetak
Biomolecular machines exploit the energy derived from ATP hydrolysis to perform complex tasks, such as the directional transport of substances within cells.[1] The realization of an artificial molecular transporter is a challenge in nanoscience and can have an impact on technological and biomedical applications.[2] Here we present the design and synthesis of a nanoscale molecular transporter that uses light as the energy source. The system is based on the repetition of photoisomerizable “pumpmodules” (Figure 1, b) inspired from pseudorotaxane-based supramolecular pumps developed recently in our group.[3] In these pumps, the E ⇆ Z photoisomerization of an azobenzene unit in a molecular axle causes the directional threading and dethreading of a crown ether ring (Figure 1, a). We envisage that, thanks to the action of a few photoactive pumps connected in series, molecular rings could be moved unidirectionally along a molecular track. The macrocycles may be functionalized with a cargo, or with a unit capable of signaling the position of the ring on the axle. A dimeric prototype of the track has been synthetized in order to investigate, in a preliminary system, the effective transport of rings under light irradiation. The ability of the device to operate away from equilibrium upon illumination is also being studied.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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