Naslov
The role of emerging and neglected viruses in the etiology of hepatitis
(The role of emerging and neglected viruses in the etiology of hepatitis)

Autori
Mrzljak, Anna ; Tabain, Irena ; Premac, Hrvoje ; Bogdanić, Maja ; Barbić, Ljubo ; Savić, Vladimir ; Stevanović, Vladimir ; Jelić, Ana ; Mikulić, Danko ; Vilibić-Čavlek, Tatjana

Izvornik
Current Infectious Disease Reports (1523-3847) 21 (2019), 12; 51, 10

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, stručni

Ključne riječi
adenoviruses ; anelloviruses ; arboviruses ; arenaviruses ; hepatitis E virus ; hepatotropic viruses ; human bocavirus ; parvovirus B19 ; pegiviruses

Sažetak
Purpose of Review: In this review, we present the overview of emerging and neglected viruses associated with liver involvement. Recent Finding: Hepatitis E virus (HEV) emerged in the last two decades, causing hepatitis in many parts of the world. Moreover, liver involvement was also described in some emerging arboviral infections. Many reports showed dengue associated liver injury ; however, chikungunya, West Nile, tick-borne encephalitis, and Zika virus are rarely associated with clinically manifest liver disease. In addition, some neglected highly prevalent viruses such as adenoviruses and parvovirus B19 are capable of causing hepatitis in specific population groups. Anelloviruses (torque teno virus/torque teno mini virus/torque teno midi virus, SEN virus), human bocavirus, pegiviruses, and lymphocytic choriomeningitis virus have shown a little potential for causing hepatitis, but their role in the etiology of liver disease remains to be determined. Summary: In addition to the well-known hepatotropic viruses, many emerging and neglected viruses have been associated with liver diseases. The number of emerging zoonotic viruses has been increasingly recognized. While zoonotic potential of HEV is well documented, the recent identification of new hepatitis- related animal viruses such as HEV strains from rabbits and camels, nonprimate hepaciviruses in domestic dogs and horses, as well as equine and porcine pegivirus highlights the possible zoonotic transmission in the context of “One Health.” However, zoonotic potential and hepatotropism of animal hepatitis viruses remain to be determined.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA