Naslov
Papillary Thyroid Carcinoma Arising within a Mature Cystic Teratoma of the Ovary: A Report of Two Cases with Long-Term Follow Up

Autori
Klarić, Marko ; Babarović, Emina ; Eminović, Senija ; Mihaljević Ferari, Ani ; Brnčić- Fischer, Alemka ; Haller, Herman

Izvornik
ARS Journal of Gynecology and obstetritics (2456-0561) 3 (2018), 1; 18-23

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Malignant transformation ; mature cystic teratoma ; papillary thyroid carcinoma ; ovary ; treatment ; Gynecology ; Obstetrics

Sažetak
Objectives: To report two patients with papillary thyroid carcinoma arising within mature cystic teratoma with long term follow- up. Methods: The cases are compared with previous reports of similar entities, with special reference to the treatment modalities and management options in follow-up of these patients. Results: Final diagnosis of both tumors was established after the initial surgery. Both tumors were histologically classified as the malignant transformation of the thyroid tissue within the mature cystic teratoma, both were papillary type and confined to one ovary. We presented two similar cases, but our therapeutic approach was surgically different. Both patients were treated with surgery alone and are alive with no evidence of the disease after 10 and 5 years, respectively. Conclusion: Preoperative and intraoperative frozen section diagnosis of malignant transformation within teratoma is very difficult, so optimal management of the patients has not yet been established. Treatment of this tumor should be individualized, but a contour of treatment modalities and management options are visible and our cases may contribute in this achievement.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA