Pregled bibliografske jedinice broj: 1046701
Advances in Desmuramyl Peptide Research
Advances in Desmuramyl Peptide Research // Croatica chemica acta, 92 (2019), 2; 153-161 doi:10.5562/cca3556 (međunarodna recenzija, pregledni rad, znanstveni)
CROSBI ID: 1046701 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Advances in Desmuramyl Peptide Research
Autori
Ribić, Rosana ; Paurević, Marija ; Tomić, Srđanka
Izvornik
Croatica chemica acta (0011-1643) 92
(2019), 2;
153-161
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni
Ključne riječi
adjuvant ; desmuramyl peptides ; immunostimulation ; pathogen recognition receptors
Sažetak
Immune adjuvants are added to vaccines in order to enhance the immune response to an antigen. Muramyl dipeptide, N-acetylmuramyl-L-alanyl-D-isoglutamine, is the smallest structural unit of peptidoglycans showing the immunostimulating activity. Muramyl dipeptide analogues without the hydrophilic N- acetylmuramyl moiety are called desmuramyl peptides. Here, we provide review of desmuramyl peptides which were synthesized in order to improve the pharmacological properties of parent muramyl dipeptide, including our results regarding adamantane containing derivatives. Approach for future design of novel immunostimulators based on multiple pathogen recognition receptor activation was also considered.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Temeljne medicinske znanosti
POVEZANOST RADA
Ustanove:
Prirodoslovno-matematički fakultet, Zagreb,
Sveučilište J. J. Strossmayera u Osijeku,
Sveučilište Sjever, Koprivnica
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
