Pregled bibliografske jedinice broj: 1041056
Spinal cord neural stem cells heterogeneity in postnatal development
Spinal cord neural stem cells heterogeneity in postnatal development // STEMedicine, 1 (2020), 1; 10.37175, 6 doi:10.37175/stemedicine.v1i1.19 (međunarodna recenzija, pregledni rad, znanstveni)
CROSBI ID: 1041056 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Spinal cord neural stem cells heterogeneity in
postnatal development
Autori
Ban, Jelena ; Mladinić, Miranda
Izvornik
STEMedicine (2705-1188) 1
(2020), 1;
10.37175, 6
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni
Ključne riječi
Neural stem cells ; Radial glia ; Ependymal cells ; Development ; Spinal cord injury
Sažetak
Neural stem cells are capable of generating new neurons during development as well as in the adulthood and represent one of the most promising tools to replace lost or damaged neurons after injury or neurodegenerative disease. Unlike the brain, neurogenesis in the adult spinal cord is poorly explored and the comprehensive characterization of the cells that constitute stem cell neurogenic niche is still missing. Moreover, the terminology used to specify developmental and/or anatomical CNS regions, where neurogenesis in the spinal cord occurs, is not consensual and the analogy with the brain is often unclear. In this review, we will try to describe the heterogeneity of the stem cell types in the spinal cord ependymal zone, based on their origin and stem cell potential. We will also consider specific animal in vitro models that could be useful to identify “the right” stem cell candidate for cell replacement therapies.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Interdisciplinarne prirodne znanosti
Napomena
Prvo izdanje časopisa STEMedicine
POVEZANOST RADA
Projekti:
UNIRI 8.12.2.1.01
18-258-6427
18-290-1463
HRZZ-IP-2016-06-7060 - Istraživanje granice između neurodegeneracije i neuroregeneracije: identifikacija ključnih molekula pomoću proteomike i funkcionalnih testova na leđnoj moždini sisavaca (DefineREgenAgeMode) (Mladinić Pejatović, Miranda, HRZZ - 2016-06) ( CroRIS)
Ustanove:
Sveučilište u Rijeci - Odjel za biotehnologiju