Pregled bibliografske jedinice broj: 1040167
Secondary Metabolites from Gorgonian Corals of the Genus Eunicella: Structural Characterizations, Biological Activities, and Synthetic Approaches
Secondary Metabolites from Gorgonian Corals of the Genus Eunicella: Structural Characterizations, Biological Activities, and Synthetic Approaches // Molecules, 25 (2020), 1; 129, 26 doi:10.3390/molecules25010129 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 1040167 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Secondary Metabolites from Gorgonian Corals of the Genus Eunicella: Structural Characterizations, Biological Activities, and Synthetic Approaches
Autori
Matulja, Dario ; Kolympadi Markovic, Maria ; Ambrožić, Gabriela ; Laclef, Sylvain ; Kraljević Pavelić, Sandra ; Marković, Dean
Izvornik
Molecules (1420-3049) 25
(2020), 1;
129, 26
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Eunicella genus ; eunicellin-type diterpenes ; sterols ; nitrogenated compounds ; cytotoxic ; anti-inflammatory ; antimicrobial ; synthetic approaches
Sažetak
Gorgonian corals, which belong to the genus Eunicella, are known as natural sources of diverse compounds with unique structural characteristics and interesting bioactivities both in vitro and in vivo. This review is focused primarily on the secondary metabolites isolated from various Eunicella species. The chemical structures of 64 compounds were divided into three main groups and comprehensively presented: a) terpenoids, b) sterols, and c) alkaloids and nucleosides. The observed biological activities of depicted metabolites with an impact on cytotoxic, anti- inflammatory, and antimicrobial activities were reviewed. The most promising biological activities of certain metabolites point to potential candidates for further development in pharmaceutical, cosmetic, and other industries, and are highlighted. Total synthesis or the synthetic approaches towards the desired skeletons or natural products are also summarized.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Biotehnologija
POVEZANOST RADA
Projekti:
IP-2016-06-3568 - Preparation of Porous Thin-film Materials for water Purification using Atomic Layer Deposition (ALD) (WATPUR) (Ambrožić, Gabriela, HRZZ - 2016-06) ( CroRIS)
EK-KF-KK.01.1.1.01.0002 - Bioprospecting Jadranskog mora (Jerković, Igor; Dragović-Uzelac, Verica; Šantek, Božidar; Čož-Rakovac, Rozelinda; Kraljević Pavelić, Sandra; Jokić, Stela, EK ) ( CroRIS)
NadSve-Sveučilište u Rijeci-uniri-prirod-18-102 - Razvoj novih nanotehnološki unaprijeđenih materijala otpornih na stvaranje bakterijskih biofilmova (Marković, Dean, NadSve ) ( CroRIS)
UNIRI-biomed-18-133 (1277)
KK.01.1.1.01
Ustanove:
Sveučilište u Rijeci - Odjel za fiziku,
Sveučilište u Rijeci - Odjel za biotehnologiju
Profili:
Dean Marković
(autor)
Sandra Kraljević Pavelić
(autor)
Maria Kolympadi Markovic
(autor)
Gabriela Ambrožić
(autor)
Dario Matulja
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE