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Pregled bibliografske jedinice broj: 1040167

Secondary Metabolites from Gorgonian Corals of the Genus Eunicella: Structural Characterizations, Biological Activities, and Synthetic Approaches


Matulja, Dario; Kolympadi Markovic, Maria; Ambrožić, Gabriela; Laclef, Sylvain; Kraljević Pavelić, Sandra; Marković, Dean
Secondary Metabolites from Gorgonian Corals of the Genus Eunicella: Structural Characterizations, Biological Activities, and Synthetic Approaches // Molecules, 25 (2020), 1; 129, 26 doi:10.3390/molecules25010129 (međunarodna recenzija, članak, znanstveni)


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Naslov
Secondary Metabolites from Gorgonian Corals of the Genus Eunicella: Structural Characterizations, Biological Activities, and Synthetic Approaches

Autori
Matulja, Dario ; Kolympadi Markovic, Maria ; Ambrožić, Gabriela ; Laclef, Sylvain ; Kraljević Pavelić, Sandra ; Marković, Dean

Izvornik
Molecules (1420-3049) 25 (2020), 1; 129, 26

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Eunicella genus ; eunicellin-type diterpenes ; sterols ; nitrogenated compounds ; cytotoxic ; anti-inflammatory ; antimicrobial ; synthetic approaches

Sažetak
Gorgonian corals, which belong to the genus Eunicella, are known as natural sources of diverse compounds with unique structural characteristics and interesting bioactivities both in vitro and in vivo. This review is focused primarily on the secondary metabolites isolated from various Eunicella species. The chemical structures of 64 compounds were divided into three main groups and comprehensively presented: a) terpenoids, b) sterols, and c) alkaloids and nucleosides. The observed biological activities of depicted metabolites with an impact on cytotoxic, anti- inflammatory, and antimicrobial activities were reviewed. The most promising biological activities of certain metabolites point to potential candidates for further development in pharmaceutical, cosmetic, and other industries, and are highlighted. Total synthesis or the synthetic approaches towards the desired skeletons or natural products are also summarized.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biotehnologija



POVEZANOST RADA


Projekti:
IP-2016-06-3568 - Preparation of Porous Thin-film Materials for water Purification using Atomic Layer Deposition (ALD) (WATPUR) (Ambrožić, Gabriela, HRZZ - 2016-06) ( CroRIS)
EK-KF-KK.01.1.1.01.0002 - Bioprospecting Jadranskog mora (Jerković, Igor; Dragović-Uzelac, Verica; Šantek, Božidar; Čož-Rakovac, Rozelinda; Kraljević Pavelić, Sandra; Jokić, Stela, EK ) ( CroRIS)
NadSve-Sveučilište u Rijeci-uniri-prirod-18-102 - Razvoj novih nanotehnološki unaprijeđenih materijala otpornih na stvaranje bakterijskih biofilmova (Marković, Dean, NadSve ) ( CroRIS)
UNIRI-biomed-18-133 (1277)
KK.01.1.1.01

Ustanove:
Sveučilište u Rijeci - Odjel za fiziku,
Sveučilište u Rijeci - Odjel za biotehnologiju

Poveznice na cjeloviti tekst rada:

doi www.mdpi.com

Citiraj ovu publikaciju:

Matulja, Dario; Kolympadi Markovic, Maria; Ambrožić, Gabriela; Laclef, Sylvain; Kraljević Pavelić, Sandra; Marković, Dean
Secondary Metabolites from Gorgonian Corals of the Genus Eunicella: Structural Characterizations, Biological Activities, and Synthetic Approaches // Molecules, 25 (2020), 1; 129, 26 doi:10.3390/molecules25010129 (međunarodna recenzija, članak, znanstveni)
Matulja, D., Kolympadi Markovic, M., Ambrožić, G., Laclef, S., Kraljević Pavelić, S. & Marković, D. (2020) Secondary Metabolites from Gorgonian Corals of the Genus Eunicella: Structural Characterizations, Biological Activities, and Synthetic Approaches. Molecules, 25 (1), 129, 26 doi:10.3390/molecules25010129.
@article{article, author = {Matulja, Dario and Kolympadi Markovic, Maria and Ambro\v{z}i\'{c}, Gabriela and Laclef, Sylvain and Kraljevi\'{c} Paveli\'{c}, Sandra and Markovi\'{c}, Dean}, year = {2020}, pages = {26}, DOI = {10.3390/molecules25010129}, chapter = {129}, keywords = {Eunicella genus, eunicellin-type diterpenes, sterols, nitrogenated compounds, cytotoxic, anti-inflammatory, antimicrobial, synthetic approaches}, journal = {Molecules}, doi = {10.3390/molecules25010129}, volume = {25}, number = {1}, issn = {1420-3049}, title = {Secondary Metabolites from Gorgonian Corals of the Genus Eunicella: Structural Characterizations, Biological Activities, and Synthetic Approaches}, keyword = {Eunicella genus, eunicellin-type diterpenes, sterols, nitrogenated compounds, cytotoxic, anti-inflammatory, antimicrobial, synthetic approaches}, chapternumber = {129} }
@article{article, author = {Matulja, Dario and Kolympadi Markovic, Maria and Ambro\v{z}i\'{c}, Gabriela and Laclef, Sylvain and Kraljevi\'{c} Paveli\'{c}, Sandra and Markovi\'{c}, Dean}, year = {2020}, pages = {26}, DOI = {10.3390/molecules25010129}, chapter = {129}, keywords = {Eunicella genus, eunicellin-type diterpenes, sterols, nitrogenated compounds, cytotoxic, anti-inflammatory, antimicrobial, synthetic approaches}, journal = {Molecules}, doi = {10.3390/molecules25010129}, volume = {25}, number = {1}, issn = {1420-3049}, title = {Secondary Metabolites from Gorgonian Corals of the Genus Eunicella: Structural Characterizations, Biological Activities, and Synthetic Approaches}, keyword = {Eunicella genus, eunicellin-type diterpenes, sterols, nitrogenated compounds, cytotoxic, anti-inflammatory, antimicrobial, synthetic approaches}, chapternumber = {129} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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