Naslov
Helicobacter pylori resistance to antibiotics in Primorsko-Goranska County

Autori
Bubonja Šonje, Marina ; Gregorović-Kesovija, Palmira ; Ambrožić, Damir ; Pružinec-Popović, Blanka ; Abram, Maja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Skup
12. Hrvatski kongres kliničke mikrobiologije ; 9. Hrvatski kongres o infektivnim bolestima (CROCMID 2019)

Mjesto i datum
Split, Hrvatska, 24.10.2019. - 27.10.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
Helicobacter pylori, antibiotics, resistance

Sažetak
High resistance rates to clarithromycin and metronidazole revealed in H. pylori strains isolated from patients in Primorsko-Goranska County provides important information that triple therapies based on these drugs are not useful as first-line treatment in this region. The regional rates of H. pylori resistance to amoxicillin and tetracycline are very low and stable during the study period which suggests that these antibiotics should be utilized in the initial treatment regimens. Increasing levofloxacin resistance, together with worrying appearance of multidrug resistance found in ten percent of clinical isolates indicate necessity of H. pylori susceptibility testing in order to guide "rescue" treatment in patients who have failed two prior treatment regimens which are typically chosen empirically. Surveillance of local antimicrobial resistance is crucial to accurately evaluate resistance rates for the optimization of both regional and personalized H. pylori treatment strategies

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA