Naslov
Maternal genetic ancestry of Croats: population genetics and forensic perspective

Autori
Barbarić, Lucija ; Zimmermann, Bettina ; Lipovac, Korana ; Sukser, Viktorija ; Rožić, Sara ; Korolija, Marina ; Parson, Walther

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
The 28th Congress of the International Society of Forensic Genetics

Mjesto i datum
Prag, Češka Republika, 09.09.2019. - 13.09.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
maternal lineages ; Croatia ; Southeast Europe

Sažetak
Present-day Croatia, a country of Southeastern Europe, is characterized by homogenous ethnic composition and complex demographic history. In order to evaluate Croatian maternal lineages and to establish the national forensic mitochondrial DNA (mtDNA) reference database, complete control region (CR) sequences were obtained from 200 randomly selected individuals. In total, 156 different haplotypes were found, which represent a haplotype diversity of 0.9984 and a random match probability of 0.66%. Moreover, Croatian mitochondrial pool is defined by Westeurasian lineages, except for one sample classified into East Asian lineage A. The most common haplogroups were H (25.5%), U (22%), followed by T (10%), K, J, R (7.5% each) and HV (6%), which accounted for almost 90% of the total variability. Results confirmed the hypothesis that mtDNA profiles of Croats resemble those of their geographical neighbors. Besides population genetic studies, the dataset will be used in mtDNA applications in forensic and missing persons casework.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti

POVEZANOST RADA