Naslov
Choosing antidepressant in breastfeeding mother – the influence of infant's condition

Autori
Makarić, Porin ; Bošnjak Kuharić, Dina ; Sabo, Tamara ; Vidović, Anđelko ; Brečić, Petrana ; Jendričko, Tihana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Skup
7th Croatian psychiatric congress with international participation and 15th Croatian psychiatric days

Mjesto i datum
Opatija, Hrvatska, 24.10.2018. - 27.10.2018

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
antidepressant ; pregnancy ; breastfeeding ; infant

Sažetak
Aim: According to previous literature, breastfeeding has long‐term benefits on child physical health and cognitive developmen. Mother’s decision to breastfeed could be influenced by the safety of a drug taken during breastfeeding because psychotropic drugs are excreted in breast milk to varying degrees. A mother’s well-being has a direct influence on the well-being of the baby so an individual risk-benefit assessment of a proposed treatment should always be performed. Our aim is to present you the complexity of choosing a right medication for mother diagnosed with postpartum depression with suicidal thoughts that breastfed a child with severe somatic complications. Methods: A case report and review of literature. Results: A 38-year-old female patient who was previously in psychotherapeutic treatment for anxiety symptoms developed severe postpartum depression with suicidal thoughts. Deterioration of her mental state was induced by severe neurological and somatic complications of her infant which is still vitally endangered. Pharmacological treatment was necessary but treatment options were limited because she wanted to continue with breastfeeding. Although Selective serotonin reuptake inhibitors are most commonly prescribed antidepressants during pregnancy and breastfeeding, they were contraindicated for our patient due to previous infant’s severe brain haemorrhage. Considering previous reports in literature, we excluded most of antidepressants due to their work mechanism or side-effect profile. Despite limited clinical data for trazodone use during breastfeeding, he was a drug of choice as it produces low levels in breastmilk and does not induce haemorrhage. Conclusion: In specific cases like this with severe clinical presentation and limiting possible side-effects where we do not have ideal medication for our patient, we have to choose the one with the lowest potential risk.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA