Naslov
Alterations of regional cerebral blood flow and emotional recognition in patients with first episode psychosis

Autori
Makarić, Porin ; Bošnjak, Dina ; Živković, Maja ; Savić, Aleksandar ; Brečić, Petrana ; Jukić, Vlado ; Madžarac, Zoran ; Petrović, Ratimir ; Rojnić Kuzman, Martina

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
European Psychiatry. 2018 ; 56(Suppl.) / Fiorillo, Andrea - Nica : Elsevier, 2018, S329-S330

Skup
26th European Congress of Psychiatry

Mjesto i datum
Nica, Francuska, 03.03.2018. - 06.03.2018

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
SPECT ; emotional recognition ; first-episode psychosis

Sažetak
Introduction: Alterations of regional cerebral blood flow (rCBF) have been observed in patients with schizophrenia, even in the First episode of psychosis (FEP). However, these alterations have been associated with psychopathology inconsistently. Objectives: To analyse the relationship of the rCBF alterations, psychopathology status and emotional recognition in FEP during acute phase. Methods: We conducted a cross-sectional study on 40 patients with FEP at the acute phase of illness during their hospitalization at Zagreb University Hospital Centre. Assessment included Single-photon emission computed tomography (SPECT), Penn emotion recognition task and Positive and Negative Syndrome Scale (PANSS). Results: While our results showed hypoperfusion of rCBF in various brain regions, there was no statistically significant correlation of rCBF with emotional recognition. Correct recognition of fear was in statistically significant negative correlation with the severity of psychopathology in general and overall PANSS scales (P < 0.01). Conclusion: Emotion recognition seems to be affected by psychopathology status. However, the link of emotional recognition deficits and alterations of rCBF is still unclear.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA