Pregled bibliografske jedinice broj: 1033834
Biomarkers in schizophrenia: protocol for follow-up study of patients with first episode psychosis
Biomarkers in schizophrenia: protocol for follow-up study of patients with first episode psychosis // European Psychiatry / Fiorillo, Andrea (ur.).
Varšava: Elsevier, 2019. str. S716-S717 (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 1033834 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Biomarkers in schizophrenia: protocol for follow-up study of patients with first episode psychosis
Autori
Makarić, Porin ; Bošnjak Kuharić, Dina ; Kekin, Ivana ; Madžarac, Zoran ; Savić, Aleksandar ; Silić, Ante ; Ostojić, Draženka ; Šagud, Marina ; Brečić, Petrana ; Jukić, Vlado ; Rojnić Kuzman, Martina
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
European Psychiatry
/ Fiorillo, Andrea - Varšava : Elsevier, 2019, S716-S717
Skup
27th European Congress of Psychiatry
Mjesto i datum
Varšava, Poljska, 06.04.2019. - 09.04.2019
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
schizophrenia ; first episode psychosis ; biological markers ; neurocognition ; TCD ; SPECT ; stress ; cortisole
Sažetak
Introduction: Huge efforts have been made to identify a biological correlate of schizophrenia in order to confirm the diagnosis and predict the outcome, but there are still no reliable biological markers. Our aim was to investigate possible clinical, functional and structural biomarkers of schizophrenia which are present during the first episode and monitor their changes during time. Methods: We have conducted a longitudinal study in patients with first episode of psychosis (FEP) and healthy controls (HC). Assessment included clinical interview, sociodemographic questionnaire, psychiatric rating scales and questionnaires and specific additional assessments that were divided into three work packages (WP). The first WP included neurocognitive and facial emotional recognition assessment with adequate tests, the second WP assessment of cerebral blood flow velocity with transcranial Doppler ultrasound, and the third WP assessment of regional cerebral perfusion with single photon emission computed tomography. Patients were assessed at baseline and after 18-month follow-up and HC at one time point. Results: We shall: 1. analyse the differences between FEP and HC, 2. analyse the changes during the course of illness from baseline to the end of study, 3. perform an exploratory analysis combining the results of different tests in order to identify potential disease phenotypes and their impact on treatment outcome. Conclusion: Identifying possible biological markers could help us in better understanding of illness and its course, as well as to tailor its treatment on individual basis.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
UIP-2014-09-1245 - Biomarkeri u shizofreniji – integracija komplementarnih prisutupa u praćenju osoba s prvom psihotičnom epizodom (BIS – LF FEP) (Rojnić Kuzman, Martina) ( CroRIS)
Ustanove:
Medicinski fakultet, Zagreb,
Klinika za psihijatriju Vrapče,
KBC "Sestre Milosrdnice",
Klinički bolnički centar Zagreb
Profili:
Vlado Jukić
(autor)
Marina Šagud
(autor)
Draženka Ostojić
(autor)
Aleksandar Savić
(autor)
Martina Rojnić Kuzman
(autor)
Petrana Brečić
(autor)
Ante Silić
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- Social Science Citation Index (SSCI)
- SCI-EXP, SSCI i/ili A&HCI
- MEDLINE