Pregled bibliografske jedinice broj: 1033795
Intravitreal Bevacizumab for the Management of Age-Related Macular Degeneration
Intravitreal Bevacizumab for the Management of Age-Related Macular Degeneration // Collegium antropologicum, 32 - Supplement 2 (2008), 2; 5-7 (međunarodna recenzija, članak, ostalo)
CROSBI ID: 1033795 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Intravitreal Bevacizumab for the Management of Age-Related Macular Degeneration
Autori
Kovačević, Damir ; Čaljkušić-Mance, Tea ; Mišljenović, Tamara ; Mikuličić, Maša ; Alpeza- Dunato, Zvjezdana
Izvornik
Collegium antropologicum (0350-6134) 32 - Supplement 2
(2008), 2;
5-7
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo
Ključne riječi
bevacizumab ; choroidal neovascularization ; age-related macular degeneration
Sažetak
The aim of this study is to report short-term effect of the treatment of »wet« ARMD (age- related macular degeneration) with intravitreal bevacizumab (Avastin). Prospective study included 36 patients (36 eyes) with »wet« form of ARMD. All patients were over 60 year old (22 female, 14 male). Changes of macula included minimally classic CNV (choroidal neovascularisation) (24), occult subfoveal CNV (10) and first stage of cicatrial CNV (2). Bevacizumab 1.25 mg was administered intravitreally through pars plana using a 27- gauge needle. Patients had no previous eye treatment. Ophthalmic exam before and after the treatment included: Snellen VA (visual acuity) and examination including measurement of IOP (intraocular pressure), FA (fluorescein angiography) and interview with patients. After 4–6 weeks 28 (78%) patients had significant improvement of VA. Median VA improved from 0.083 to 0.200 (p<0.01). Eight patients (22%) had no significant improvement in VA but three of them reported to see more light. FA showed complete resolution of macular edema in 6 patients (17%), partially resolved in 23 patients (64%) and no change in 7 patients (19%). No systemic side-effect was found. Short-term results suggest that intravitreally administered bevacizumab is well tolerated treatment for ARMD with very high number of patients showing improvement in VA.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Social Science Citation Index (SSCI)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE