Naslov
Pathohistological characteristics of gingival tissue in orthodontic patients with nickel and titanium allergies

Autori
Žigante, Martina ; Matušan Ilijaš, Koviljka ; Peternel, Sandra ; Rinčić Mlinarić, Marijana ; Špalj, Stjepan

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
European Journal of Orthodontics. Abstracts of Lectures and Scientific Posters. 2019 ; 41:e1-e189 / - Nica, 2019

Skup
95th Congress of the European Orthodontic Society

Mjesto i datum
Nica, Francuska, 17.06.2019. - 22.06.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
titanium ; nickel ; allergy ; orthodontic treatment

Sažetak
AIMS: Nickel (Ni) and titanium (Ti) are constituent elements of orthodontic alloys and both can cause contact allergic stomatitis. The spectrum of signs and symptoms of oral contact allergy is wide. There is no single pathognomonic sign or specific clinical picture. The aim of this research was to assess the pathohistological changes in gingival tissue in orthodontically treated patients with an allergy to Ni and/or Ti. SUBJECTS AND METHOD: Patients undergoing orthodontic therapy with gingival hyperplasia were subjected to initial periodontal therapy. In those with persisting gingival enlargement after initial periodontal therapy, an external gingivectomy was performed (N = 29). Gingival fragments were processed with the paraffin- embedding histological technique and stained with haematoxylineosin. Allergy to Ni and Ti was diagnosed after performing a patch test on the upper arm skin. Allergens included nickel sulphate, titanium, titanium dioxide, titanium oxalate, titanium nitride and petrolatum as the control. RESULTS: An allergy was present in 35 per cent of the subjects. The gingiva of allergic subjects demonstrated a slightly higher severity of inflammation and fibrosis, somewhat more frequently epithelial changes (mild hyperplasia, spongiosis but also colliquation of basal layers), and focal inflammatory infiltrates. Also, in allergic subjects inflammation was often localized near the basal membrane. Lymphocytes, histiocytes, plasma cells, eosinophils and neutrophils were present. However, the majority of pathohistological findings did not differ between groups at a statistically significant level. Pronounced exocytosis and band-like inflammatory infiltrates were significantly more often present in allergic subjects (P < 0.05). CONCLUSION: The presence of exocytosis and band- like inflammatory infiltrates appear to be the most characteristic signs of allergy to Ni and Ti in gingival tissue.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Dentalna medicina

POVEZANOST RADA