Naslov
Use of dermatoscopy in the detection of squamous cell carcinoma in a patient with recessive dystrophic epidermolysis bullosa

Autori
Jurakić Tončić, Ružica ; Petković, Mikela ; Murat-Sušić, Slobodna ; Čeović, Romana ; Argenziano, Giuseppe

Izvornik
Dermatology Practical & Conceptual (2160-9381) 8 (2018), 3; 227-230

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, prikaz slučaja, znanstveni

Ključne riječi
dermoscopy ; nonmelanoma skin cancer ; severe generalized recessive dystrophic bullous epidermolysis ; squamous cell carcinoma

Sažetak
Epidermolysis bullosa (EB) is a heterogeneous group of disorders. Inherited EB is classified into EB simplex, junctional, and dystrophic [1]. We present a case of a 33- year-old female patient with severe generalized recessive dystrophic epidermolysis bullosa (RDEB-SG) who, since birth, has received follow-up in our Department and Referral Centre of the Ministry of Health and Social Welfare of the Republic of Croatia for hereditary bullous epidermolysis. She presented with 5 non-healing lesions on the scalp, which were clinically very suggestive of squamous cell carcinoma (SCC). A year ago, the patient underwent surgical removal of a well-differentiated SCC in the occipital region and moderately differentiated SCC in the left parietotemporal region. Clinically, in the occipital region, next to the margin of cutaneous flap of previously excised SCC, exophytic lesions and ulcerations were found. In the left parietotemporal region, an erosion measuring 3 cm in diameter with an elevated margin was found (Figure 1). Dermoscopy was performed on 5 regions that clinically presented as ulcerations and revealed a red background. Lesions presented with an amorphous whitish or pinkish background along with polymorphous atypical vessels (Figure 2). In some areas, erosions were clearly seen. Histopathology confirmed diagnosis of moderately differentiated SCC in all 5 lesions.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA