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Anisakis spp. genomic epidemiology - scratching the surface of an emerging zoonosis (CROSBI ID 675919)

Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija

Mladineo, Ivona ; Trumbić, Željka ; Bušelić Garber, Ivana ; Hrabar, Jerko ; Vrbatović, Anamarija Anisakis spp. genomic epidemiology - scratching the surface of an emerging zoonosis // Molecular Helminthology: An Integrated Approach Abstract Book / LoVerde, Phillip T. ; Lustigman, Sara (ur.). Elsevier, 2019. str. 1-1

Podaci o odgovornosti

Mladineo, Ivona ; Trumbić, Željka ; Bušelić Garber, Ivana ; Hrabar, Jerko ; Vrbatović, Anamarija

engleski

Anisakis spp. genomic epidemiology - scratching the surface of an emerging zoonosis

Global migration and trade of the foodstuff, climate change, novel trends in human eating habits characterised by an elevated demand for raw food, are considered as major reasons why reports of food borne infections, especially zoonotic parasitosis, have increased in the last decade. Consequently, health authorities and fishing industry have increasingly become aware of the significance of nematode genus Anisakis, which affects human health and the commercial value of fish products. Adriatic fish, marketed fresh, frozen, salted or marinated and exported to EC, are frequently rejected on the border because of Anisakis infection. Although considered one of the most significant emerging food-borne zoonosis, anisakiasis in many Mediterranean countries is still misdiagnosed or underestimated. During a four-year research within the project AnGEl (Anisakis spp: Genomic Epidemiology) funded by the Croatian Science Foundation, we have assessed Anisakis using a multidisciplinary approach, studying the fish as paratenic, cetaceans as the final and men as accidental host. The project resulted in new knowledge on: i) molecular geo-distribution of Anisakis spp. and its hybrids in the Adriatic Sea fish inferred by a newly developed genome-derived small sequence repeats (SSR) tool ; ii) the histopathological effect of the nematode in the digestive tract of the paratenic, final and the model accidental host inferred by IHC and TEM ; iii) the nematode transciptomic signature during migration through the model host using RNAseq and microRNA quantification ; iv) traits of the larval multixenobiotic resistance mechanisms that will help to design more effective therapy ; v) anti-Anisakis IgE seroprevalence in human population professionally related to the fish processing industry. The most important results will be presented, aiming to trigger better conscience and take home message about this emerging and highly under- and missdiagnosed zoonosis.

Anisakis, fish, cetacean, human

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Podaci o prilogu

1-1.

2019.

objavljeno

Podaci o matičnoj publikaciji

Molecular Helminthology: An Integrated Approach Abstract Book

LoVerde, Phillip T. ; Lustigman, Sara

Elsevier

Podaci o skupu

Molecular Helminthology: An Integrated Approach

predavanje

07.04.2019-10.04.2019

San Antonio (TX), Sjedinjene Američke Države

Povezanost rada

Biologija, Veterinarska medicina, Biotehnologija