engleski

Investigating of silica-cinnamon hybrid materials – preparation and characterization for medical application

Silica-cinnamon hybrid materials were prepared and characterized as a potential new material for medical application - medical textiles, i.e. wound dressings. For the treatment of chronic wound a large number of wound dressings of various structural characteristics and mechanisms of action are used. Wound dressings made using the most modern textile processes with the addition of antimicrobial agents. Most of them are based on high performance fabrics in form of non-woven with different collagen products, alginate fibres or hydrogels with antimicrobial compounds such as silver, betaine, chitin, etc. to try to both protect the healing wound from infection and also to help promote the wound healing process itself. Some of new research in wound healing have focused on novel molecules of interest such as nitric oxide but for some chronic wounds the answer could be in the nature with naturally compounds honey, curcuma, aloe vera, cinnamon, garlic, peppermint oil, etc. Cinnamomum verum (cinnamon) contain compounds with a wide range of proven antibacterial, antiviral, antipyretic, anti-inflammatory and antifungal properties. Silica-cinnamon cotton fabrics were prepared by dip-coating from 3-glycidyloxypropyltrimethoxysilane (GLYMO) as a precursor with catalyst and with commercially available powder of cinnamon. The aim was to achieve cinnamon evenly distributed and represented along the fibres, still present in sufficiently quantity after laundering. The coatings were characterized by infrared spectroscopy (FTIR-ATR), scanning electron microscopy (SEM) and crease recovery angle. Determination of antibacterial activity was performed by agar diffusion plate test to Staphylococcus and Escherichia coli.

Sol-gel, medical textiles, natural compounds, nanoparticles

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