engleski

Croatian Registry on AMBULATORY BLOOD PRESSURE MONITORING (HRKMAT). Preliminary Report on Basic Characteristics of Study Population

OBJECTIVE: To analyse characteristics of the subjects included in the Croatian national registry on ambulatory blood pressure monitoring (ABPM). DESIGN AND METHOD: Out of 1637 subjects included so far in the national registry, data on 1399 participants (men 55% ; median age 59) were analysed. ABPM was performed to each subject. Anthropometric measurements (height, weight, waist circumference) were determined and BMI was calculated. Medical history and data on ongoing medications were assessed. Office blood pressure (BP) was measured 3 times in a sitting position using sphygmomanometer, while heart rate (HR) was determined by palpation method ; average values of the last two measurements of both variables were taken into consideration. ABPM was measured during normal working day. RESULTS: Median and interquartile ranges of height, weight, BMI, waist circumference of the whole were respectively: 170 (163-177), 83 (74- 94), 28.7 (25.9-31.9), 99 (89-107). Office and ABPM BP and HR values are shown in table 1. Subjects reported using antihypertensive drugs as follows: one drug 13.4%, two 25.6%, three 26.1%, four 21%, and > 4 drugs 13.7%. Also 33.6% of participants were taking other medications apart from antihypertensives: 1 drug 12 %, 2 drugs 11% and 3 drugs 10.6% of subjects. BP control was achieved in 31.5% of patients. White coat hypertension (WCH) was diagnosed in 22.2% of hypertensives (42.1% men, median age 56.5 (19-88) ; masked hypertension (MH) was diagnosed in 23.7% of hypertensives (83.9% men, median age 23 (20-86). Subjects with WCH were older than those with MH (p < 0.0001). Table 1. Median and interquartile ranges of the observed variables Systolic BP Diastolic BP Heart Rate Office 143 (130-160) 90 (80-100) 72 (64-78) 24 ABPM 127 (119.5-135) 74 (68-82) 71 (64, 5-77) Day-time ABPM 130.5 (123-140) 77 (71-85) 75 (67-82) Night-time ABPM 119 (111-127) 67 (60-74) 63 (57, 8-69) CONCLUSIONS: BP control is poor in our cohort despite almost 90% were treated with drug combination. One third of hypertensive are regularly taking other medication what decreases overall adherence and effectiveness. Hypertensives have increased BMI and WC. In our registry WCH and MH represent a quite high percentage of patients with hypertension. Our analyses confirmed useful value of ABPM in regular clinical work. This first report from our registry confirmed its usefulness and results alert for action.

ambulatory blood pressure monitoring, Croatian national registry, blood pressure control

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