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Pregled bibliografske jedinice broj: 997527

First isolation and genotyping of Bartonella henselae from a cat living with a patient with cat scratch disease in Southeast Europe


Stepanić, Maja; Duvnjak, Sanja; Reil, Irena; Špičić, Silvio; Kompes, Gordan; Beck, Relja
First isolation and genotyping of Bartonella henselae from a cat living with a patient with cat scratch disease in Southeast Europe // BMC Infectious Diseases, 19 (2019), 1; 299, 6 doi:10.1186/s12879-019-3929-z (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 997527 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
First isolation and genotyping of Bartonella henselae from a cat living with a patient with cat scratch disease in Southeast Europe

Autori
Stepanić, Maja ; Duvnjak, Sanja ; Reil, Irena ; Špičić, Silvio ; Kompes, Gordan ; Beck, Relja

Izvornik
BMC Infectious Diseases (1471-2334) 19 (2019), 1; 299, 6

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Bartonella henselae ; Cat ; Cat-scratch disease ; Child ; Croatia ; Culture ; Genotyping ; MLST

Sažetak
Background: The bacterial genus Bartonella is distributed worldwide and poses a public health risk. Cat-scratch disease caused by B. henselae in Croatia was first described in 1957. It is present throughout the country: a survey of serum samples from 268 Croatian patients with lymphadenopathy showed that 37.7% had IgG antibodies. Despite this prevalence, we are unaware of reports of Bartonella culturing from infected humans or cats in Croatia or elsewhere in southeast Europe. Case presentation: Here we describe the diagnosis of a 12-year-old child with lymphadenopathy in Croatia with cat- scratch disease based on antibody detection and clinical signs, and the subsequent culturing and genotyping of B.henselae from the cat’s blood. The B. henselae isolate was grown on different blood agar plates and its identity was confirmed based on polymerase chain reaction (PCR) amplification of 16S ribosomal deoxyribonucleic acid (16S rDNA) and sequencing. Multi-locus sequence typing (MLST) identified the strain genotype as sequence type 5, commonly found zoonotic B. henselae strain in cats. The child recovered after azithromycin therapy, and B. henselae in the cat was eliminated within three months after doxycycline treatment. Conclusions: This is, to our knowledge, the first report of B. henselae culturing and MLST-based genotyping from cat’s blood in southeast Europe. Our ability to detect B. henselae in blood through culturing but not PCR suggests that the prevalence of infected cats with low bacteremia is very high, suggesting the need to develop faster, more sensitive detection assays.

Izvorni jezik
Engleski



POVEZANOST RADA


Projekt / tema
GENOTICKTRECK of the Croatian Science Foundation (project no. 1957) - GENOTICKTRECK of the Croatian Science Foundation (project no. 1957) (, )

Profili:

Avatar Url Silvio Špičić (autor)

Avatar Url Relja Beck (autor)

Avatar Url Gordan Kompes (autor)

Avatar Url Sanja Duvnjak (autor)

Citiraj ovu publikaciju

Stepanić, Maja; Duvnjak, Sanja; Reil, Irena; Špičić, Silvio; Kompes, Gordan; Beck, Relja
First isolation and genotyping of Bartonella henselae from a cat living with a patient with cat scratch disease in Southeast Europe // BMC Infectious Diseases, 19 (2019), 1; 299, 6 doi:10.1186/s12879-019-3929-z (međunarodna recenzija, članak, znanstveni)
Stepanić, M., Duvnjak, S., Reil, I., Špičić, S., Kompes, G. & Beck, R. (2019) First isolation and genotyping of Bartonella henselae from a cat living with a patient with cat scratch disease in Southeast Europe. BMC Infectious Diseases, 19 (1), 299, 6 doi:10.1186/s12879-019-3929-z.
@article{article, year = {2019}, pages = {6}, DOI = {10.1186/s12879-019-3929-z}, chapter = {299}, keywords = {Bartonella henselae, Cat, Cat-scratch disease, Child, Croatia, Culture, Genotyping, MLST}, journal = {BMC Infectious Diseases}, doi = {10.1186/s12879-019-3929-z}, volume = {19}, number = {1}, issn = {1471-2334}, title = {First isolation and genotyping of Bartonella henselae from a cat living with a patient with cat scratch disease in Southeast Europe}, keyword = {Bartonella henselae, Cat, Cat-scratch disease, Child, Croatia, Culture, Genotyping, MLST}, chapternumber = {299} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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