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Photophysical properties and photochemical reactivity of a quinone methide precursor containing BODIPY chromophore


Zlatić, Katarina; Antol, Ivana; Basarić, Nikola
Photophysical properties and photochemical reactivity of a quinone methide precursor containing BODIPY chromophore // 26th Croatian Meeting of Chemists and Chemical Engineers, Šibenik, 2019
Šibenik, Hrvatska, 2019. str. 105-105 (poster, međunarodna recenzija, sažetak, znanstveni)


Naslov
Photophysical properties and photochemical reactivity of a quinone methide precursor containing BODIPY chromophore

Autori
Zlatić, Katarina ; Antol, Ivana ; Basarić, Nikola

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
26th Croatian Meeting of Chemists and Chemical Engineers, Šibenik, 2019 / - , 2019, 105-105

Skup
26th Croatian Meeting of Chemists and Chemical Engineers, Šibenik, 2019

Mjesto i datum
Šibenik, Hrvatska, 9-12.04.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
BODIPY, quinonemethide, photodeamination

Sažetak
BODIPY® is a tradename for a class of compounds containing a 4, 4‐difluoro‐4‐bora‐3a, 4adiaza‐ s‐indacene group. BODIPY derivatives are commonly used as dyes for biomolecular labeling since they are characterized by good photochemical stability and excellent photophysical and spectral properties [1]. On the other hand, quinone methides (QM) are reactive intermediates that can be generated in photochemical reactions, [2] that exhibit biological activity, which is related to their ability to alkylate DNA [3]. The objective of our research is to combine these two groups in one molecule and to develop potential photoactivable anticancer drugs [4]. Herein we present a study of photochemical reactivity for BODIPY quinone methide precursor molecule 1. Its photophysical properties were investigated by steady‐state and time resolved fluorescence. The photochemical reactivity was investigated by irradiations in CH3OH solution at different wavelengths. Interestingly, the photochemical reactivity is dependent on the wavelength used for irradiation, contrary to the Kasha photochemical law. The experimental observations were backed up by TD‐DFT calculations

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekt / tema
HRZZ-IP-2014-09-6312 - Supramolekulska kontrola fotokemijskih reakcija eliminacije (Nikola Basarić, )

Ustanove
Institut "Ruđer Bošković", Zagreb