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Pregled bibliografske jedinice broj: 996165

Red cell distribution width in acute pulmonary embolism patients: A simple aid for improvement of the 30-day mortality risk stratification based on the pulmonary embolism severity index


Jurin, Ivana; Trkulja, Vladimir; Ajduk, Marko; Letilović, Tomislav; Hadžibegović, Irzal
Red cell distribution width in acute pulmonary embolism patients: A simple aid for improvement of the 30-day mortality risk stratification based on the pulmonary embolism severity index // Heart & Lung, 18 (2019), 5-10 doi:10.1016/j.hrtlng.2019.02.006 (međunarodna recenzija, članak, znanstveni)


Naslov
Red cell distribution width in acute pulmonary embolism patients: A simple aid for improvement of the 30-day mortality risk stratification based on the pulmonary embolism severity index

Autori
Jurin, Ivana ; Trkulja, Vladimir ; Ajduk, Marko ; Letilović, Tomislav ; Hadžibegović, Irzal

Izvornik
Heart & Lung (0147-9563) 18 (2019); 5-10

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
30-day mortality ; Acute pulmonary embolism ; Pulmonary embolism severity index ; Red cell distribution width

Sažetak
BACKGROUND: Pulmonary embolism (PE) severity index (PESI) well predicts 30-day mortality in acute PE patients, yet improvements have been advocated. OBJECTIVES: To evaluate predictivity of the red cell distribution width (RDW) through a comparison with PESI and to explore their interaction as a potential improvement in this respect. METHODS: Retrospective analysis of consecutive adult PE patients. RESULTS: Of the 299 patients, 19 severely unstable died within 48 h. Among the stabilized patients, 30- day mortality was 12.1% (34/280). With PESI ≤125, mortality was 4.9% (9/185), but it was 0.7% (1/140) if RDW ≤15.0% and 17.8% (8/45) if RDW >15.0% ; with PESI >125, mortality was 26.3% (25/95), but it was 15.9% (7/44) if RDW ≤15.0% and 35.3% (18/51) if RDW >15.0%. Adjusted relative risk with PESI >125 vs. ≤125 was 17.5 (95%CI 2.37-129) at RDW ≤15.0% and 1.60 (0.76- 3.36) at RDW >15.0%. CONCLUSIONS: Thirty-day mortality predictions based on the PESI score may be improved by accounting for RDW.

Izvorni jezik
Engleski

Znanstvena područja
Biologija



POVEZANOST RADA


Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
  • Scopus
  • MEDLINE


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