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Surfactant properties of alkyl quinuclidine-3-ols

Quaternary ammonium compounds (QACs) are group of chemical compounds with broad spectrum applications. Owing to their amphiphilic nature, QACs reduce surface tension and form micelles allowing dispersion in a liquid. Due to this ability QACs are incorporated into soaps, cosmetics, hair dyes and detergents. Previously synthesized QACs consisting of a quinuclidine-3-ol core and long side alky chains (C10, C12, C14) have shown promising antimicrobial potential and low cytotoxicity. Given their potential application, here we have additionally investigated thermodynamic properties and self-assembly of these surfactants (Figure 1.) by measuring conductivity, dynamic light scattering (DLS) and Zeta-potential.

Quaternary ammonium compounds (QAC) ; Surfactnats ; Thermodynamic properties

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