engleski

Male and Female Infertility and Periodontal Disease: Letter to The Editor

In almost one third of female and male patients which undergo infertility treatments, the casue of infertility is unknown. Recent literature results point that there might be a connection between periodontal disease and male and female infertility. Periodontal diseases are chronic infections which may lead to bacteriemia, endotoxemia, increased plasma levels of inflammatory cytokines and generalised immune dysregulation effect, resulting with negative influence on reproductive potential. Immune sensitization to microbial heat shock proteins even in the presence of asymptomatic and subclinical infection is associated with unsuccessful embryo development and implantation failure of in vitro fertilization patients. Also, ovulation drugs induce gingival inflammation which may have negative impact on the results of fertilization treatment. Literature results show that women with periodontal disease have significantly longer conception time. Some authors have found a connection of periodontal disease and sperm sub-motility. Therefore in every infertile patient (male and female) periodontal status should be checked and appropriate periodontal treatment should be performed.

male infertility ; female infertility ; periodontal disease ; chronic infection

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