Hyperspectral imaging for intraoperative diagnosis of colon cancer metastasis in a liver (CROSBI ID 674036)
Prilog sa skupa u zborniku | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Kopriva, Ivica ; Aralica, Gorana ; Popović Hadžija, Marijana ; Hadžija, Mirko ; Dion-Bertrand, Laura-Isabelle ; Chen, Xinjian
engleski
Hyperspectral imaging for intraoperative diagnosis of colon cancer metastasis in a liver
Hyperspectral imaging (HSI) is being shown as an emerging modality with a great potential in disease diagnosis and surgical cancer resection. Herein, we evaluate feasibility of the HSI to discriminate and diagnose colon cancer metastasis in a liver from five hematoxylin and eosin stained histopathological specimens. They were collected from the same patient during intraoperative frozen section analysis. Cancer and non-cancer spectra along with corresponding spatial maps were estimated from hyperspectral images by means of spectral unmixing. It was found that maximal angle between cancer spectra is 1.02 degrees less than minimal angle between cancer vs. non-cancer spectra. Thus, spectrum angle mapper was used for pixel-based diagnosis of cancer yielding sensitivity between 81.23% and 97.12%, specificity between 85.85% and 97.3%, and accuracy between 86.85% and 96.92%.
intraoperative diagnosis ; hyperspectral microscopic imaging ; liver ; colon cancer metastasis ; spectral angle mapper
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Podaci o prilogu
109560S
2019.
objavljeno
10.1117/12.2503907
Podaci o matičnoj publikaciji
SPIE Medical Imaging Symposium 2019 - Digital Pathology Conference
Tomaszewski, John ; Ward, Aaron
Bellingham (WA): SPIE
Podaci o skupu
SPIE Medical Imaging 2019
poster
16.02.2019-21.02.2019
San Diego (CA), Sjedinjene Američke Države