Nalazite se na CroRIS probnoj okolini. Ovdje evidentirani podaci neće biti pohranjeni u Informacijskom sustavu znanosti RH. Ako je ovo greška, CroRIS produkcijskoj okolini moguće je pristupi putem poveznice www.croris.hr
izvor podataka: crosbi !

Increased prevalence of celiac disease in patients with oral lichen planus (CROSBI ID 261633)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Cigić, Livia ; Gavić, Lidija ; Šimunić, Miroslav ; Ardalić, Žarko ; Biočina-Lukenda, Dolores Increased prevalence of celiac disease in patients with oral lichen planus // Clinical oral investigations, 19 (2015), 3; 627-635

Podaci o odgovornosti

Cigić, Livia ; Gavić, Lidija ; Šimunić, Miroslav ; Ardalić, Žarko ; Biočina-Lukenda, Dolores

engleski

Increased prevalence of celiac disease in patients with oral lichen planus

OBJECTIVES: The aim of this study was to establish the prevalence of celiac disease (CD) in patients with erosive and reticular form of oral lichen planus (OLP) compared to healthy controls. MATERIALS AND METHODS: Tissue transglutaminase antibodies (anti-tTG) and antibodies against gliadin (AGA) were measured in the sera from 56 OLP patients and 57 healthy controls, who also underwent human leukocyte antigen (HLA) typing. The duodenal biopsy was performed in patients with positive serology, and a gluten-free diet was recommended if CD was confirmed. RESULTS: CD was diagnosed in eight OLP patients (14.29 %). Six OLP patients (10.71 %) were positive for immunoglobulin A (IgA) tTG. A statistically significant difference among the forms of oral lichen was observed for the IgA tTG (p = 0.03) and immunoglobulin G (IgG) tTG (p = 0.01). Higher frequencies of HLA-DQ2 and HLA-DQ8 were found in OLP patients compared to the control group. CONCLUSION: The prevalence of CD was higher in patients with OLP than in the control group. Therefore, increased efforts aimed at the early detection and dietary treatment of CD, among antibody- positive OLP patients, are advisable. CLINICAL RELEVANCE: Our study confirmed the increased frequency of CD among OLP patients. CD screening should be considered in OLP patients, since untreated CD can present many complications and reduce a patient's quality of life.

celiac disease, oral lichen planus

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

Podaci o izdanju

19 (3)

2015.

627-635

objavljeno

1432-6981

1436-3771

Povezanost rada

Dentalna medicina, Kliničke medicinske znanosti

Indeksiranost