Targeting tumour metastasis: the emerging role of nanotechnology (CROSBI ID 261606)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Visentin, Sarah ; Sedić, Mirela ; Kraljević Pavelić, Sandra ; Pavelić, Krešimir
engleski
Targeting tumour metastasis: the emerging role of nanotechnology
Metastatic process has still not been completely elucidated, probably due to insufficient knowledge of the underlying mechanisms. Here, we provide an overview of the current findings that shed light on specific molecular alterations associated with metastasis and present novel concepts in the treatment of the metastatic process. In particular, we discuss novel pharmacological approaches in the clinical setting that target metastatic progression. New insights into the process of metastasis allow optimizing and designing new treatment strategies, especially when taking into account the fact that metastatic cells share common features with stem cells. Lastly, we touch upon nano- and micro-technologies in targeted drug delivery for metastatic cancer. The latter could provide more efficient way to tackle metastasis and thus bring about advancements in the treatment and management of cancer patients.
cancer stem cells ; cancer therapy ; metastasis ; nanomedicine ; stem cell marker
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Podaci o izdanju
27 (8)
2020.
1367-1381
objavljeno
0929-8673
1875-533X
10.2174/0929867326666181220095343
Povezanost rada
Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)