engleski

MRI: A new powerful tool in paleopathological differential diagnosis

Magnetic Resonance Imaging (MRI) is one of the most used imaging methods in modern medicine ; for example in 2016 United States had population rate of annual MRI scans of 118 per 1000 people. MRI in clinical settings is still undeveloped and underused in paleopatology ; it has been used only several times (in scientific study of mummies) as there aren’t enough unbound protons in dehydrated bodies. Although some efforts have been made during the ‘80s with rehydration of mummified samples, the first successful MRI of a whole dry mummy was done by Ruehli et al. in Zurich in 2007 using the ultra short echo time sequence (UTE). From 2008-2012 mummified remains from the Egyptian Collection of the Archeological Museum in Zagreb, Croatia have been scanned on Xray, CT and MRI in the University Hospital Dubrava, Zagreb, Croatia, and a case of ancient rare disease has been published in 2012 by our group. We have suggested that a young male, from the period between 950–790 B.C. was suffering from Langerhans cell histiocytosis (LCH), a rare group of disorders without well- understood aetiology. Furthermore we classified it as Hand- Schueller-Christian disease, one of three syndromes associated with LCH, which has the incidence up to 0.5 per 100000 children per year. As this was the first case of MRI use in differential diagnosis in paleopathology, we want to reassess the use of MRI in paleopathology in the context of rare diseases.

Paleoradiology, Croatia, Mummies, Archeology, Langerhans cell Histiocytosis

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