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Blood glucose level and frequency of diabetes mellitus in patients with oral lichen planus.

The main aim of this study was to examine whether there was a difference in average glucose level in blood and frequency of diabetes mellitus between patients with oral lichen planus (OLP) and those without pathological changes of the oral mucosa. Anamnestic data from every study participant (n=126) included age, gender, smoking habits and alcohol consumption and presence of diabetes mellitus. Body weight and height were determined in order to calculate body mass index (BMI). Also blood pressure was measured for every study pariticpant. Blood samples were obtained from each study participant to determine the values of glucose. Study group contained 63 participants diagnosed with OLP, whereas control group also contained 63 participants without pathological changes of oral mucosa. Average amount of glucose in blood of participants with OLP from the study group was 5, 45 , while the average amount of glucose in blood in control group was 5, 32. Average amounts were similar in both groups and there was not significant difference ( P = 0, 497 ). Increased level of glucose in blood (>6, 4 mmol/L) was measured for only four participants ( 6, 3 % ) from the study group and three participants from control group (4, 8 %). Difference between groups in frequency of diabetes mellitus was also not significant (P = 0, 198). Diabetes mellitus is suggested as a possible etiological factor in development of OLP, but exact causative relationship between these two diseases still remains unknown. Further research including more subjects are required to confirm or abrogate the findings of this study.

blood glucose, diabetes mellitus, oral lichen planus

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