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Pregled bibliografske jedinice broj: 986830

Henoch-Schonlein purpura in the third trimester of pregnancy

Djakovic, Ivka; Butorac, Dražan; Vucicevic, Zeljko; Kosec, Vesna; Tesija Kuna, Andrea; Lugović-Mihić, Liborija
Henoch-Schonlein purpura in the third trimester of pregnancy // Biochemia Medica, 28 (2018), 1; 1-5 (međunarodna recenzija, članak, znanstveni)

Henoch-Schonlein purpura in the third trimester of pregnancy

Djakovic, Ivka ; Butorac, Dražan ; Vucicevic, Zeljko ; Kosec, Vesna ; Tesija Kuna, Andrea ; Lugović-Mihić, Liborija

Biochemia Medica (1330-0962) 28 (2018), 1; 1-5

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Henoch-Schonlein purpura ; leukocytoclastic vasculitis ; pregnancy ; glomerulonephritis ; preeclampsia

Henoch-Schönlein purpura (HSP) is an IgA- mediated small vessels’ vasculitis that affects the skin, intestines and kidneys. Pregnancy has been reported as an exacerbating factor. We present the case of a 24-year-old primigravida with HSP that occurred in the third trimester and lasted up to the end of the successful delivery. She had pruritic maculopapular exanthema on her legs. Biopsy of a cutaneous lesion was performed for histopathologic features and direct immunofluorescence (DIF) for the presence of perivascular IgA deposition. Histopathology of the cutaneous lesion confirmed leukocytoclastic vasculitis. A DIF examination of the skin lesion confirmed deposits of fibrinogen in the small blood vessel walls. Six weeks following delivery, the skin lesions almost completely disappeared. Control laboratory findings were normal. This case of HSP might have been primarily associated with a preceding respiratory infection but this should first be carefully investigated due to a possible severe immunological disease in the patient’s background requiring special attention since nephrotic symptoms may occur.

Izvorni jezik

Znanstvena područja
Kliničke medicinske znanosti

Časopis indeksira:

  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus

Uključenost u ostale bibliografske baze podataka:

  • EMBASE (Excerpta Medica)
  • JCR
  • ScienceCentral