engleski

Blood pressure and outcome in acute stroke : differences between ishaemic stroke and intracerebral haemorrhage

The aim of this study is to establish the difference between BP changes and outcome in ischemic stroke (ISH) and intracerebral haemorrhage (ICH). This was a prospective study including patients with severe stroke (ISH and ICH) admitted to intensive care unit within 6 hours after stroke onset. Previous normotensive and hypertensive patients were included. BP was measured every 2 hours during first 72 hours after stroke onset. Antihypertensive therapy was administered when needed. Stroke severity was assessed using Scandinavian Stroke Scale (SSS) at the time of admission and discharge from hospital. All results are presented descriptively. Results: This study included 114 stroke patients, 60 female and 54 male, mean age 73, 1+12, 9years. There were 85 patients with ISH and 29 with ICH. Prior hypertension was present in 63% of all stroke patients, 55% in ISH and 87% in ICH group. The mean systolic arterial BP at admission was 157+16, 8mmHg in ISH and 163, 4+19, 3 mmHg in ICH patients. The follow up of systolic BP changes during first 72 hours showed continuously higher BP in ICH than in ISH patients (162, 6mmHg ; 146, 5mmHg, respectively). BP during first 72 hours in ICH group was higher in patients who died than in survivors. Higher BP was present during first 72 hours in patients with SSS < 15 at admission, while BP gradually normalized in patients with SSS>16 at admission. SSS at admission was higher in ISH (> 15) than in ICH patients (< 15). In ICH group 29% of patients died, but survivors had better SSS on discharge than survivors in ISH group. BP is very important factor in prognosis of stroke course and outcome. Hypertension is associated with poor outcome and higher mortality rate, especially in patients with ICH.

blood pressure ; stroke ; ischemic stroke ; haemorrhagic stroke

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