engleski

Shear wave elastography features of medullary breast carinoma

Medullary breast carcinoma is a very rare subtype of invasive ductal carcinomas. In our retrospective study, we analyzed shear wave elastographic features of 7 patients diagnosed with medullary carcinoma and compared them to 20 patients diagnosed with nonspecific type of invasive ductal carcinoma and 20 patients diagnosed with fibroadenoma. Quantitative (El max, El min and El mean of the stiffest part of the lesion) and qualitative ( colour of the whole lesion, colour of the rim and the shape) values of 3 groups were measured. Quantitative results showed that medullary carcinomas were stiff tumors (El mean 173, 84 ± 23, 81) but softer than invasive ductal carcinomas of nonspecific type which were all also stiff (El mean 195, 88 ± 18, 88), while fibroadenomas were soft tumors (El mean 36, 99 ± 7, 27). Qualitatively, medullary carcinomas were dominantly soft lesions (85, 7%) with the stiff rim (71, 4%) and regular shape (71, 4%), while invasive ductal carcinomas of non specific type were stiff lesions (65%) with stiff rim (65%) but an irregular shape (85%). Fibroadenomas though were in 100% soft lesions with a soft rim (95%) and regular shape (70%). According to the results, medullary carcinomas have similarities with both malignant and benign lesions. Quantitative values indicate that these carcinomas are stiff tumors just like invasive carcinomas of non specific type, contrary to fibroadenomas which are dominantly soft. Qualitatively medullary carcinomas are regularly shaped lesions which are dominantly soft just like fibroadenomas, but have a stiff rim similarly to invasive carcinomas. The conclusion of our study is that medullary carcinomas compared with two control groups have specific shear wave elastography features, meaning they are regularly shaped, soft lesions according to colour with stiff rim and high quantitative values. Elastographic features may complement mammography and conventional ultrasound in diagnosing this very rare subtype of invasive breast carcinoma.

Breast lesions, medullary breast carcinoma, elastography

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