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Pregled bibliografske jedinice broj: 978184

Ready-to-use green polyphenolic extracts from food by-products


Panić, Manuela; Radić Stojković, Marijana; Kraljić, Klara; Škevin, Dubravka; Radojčić Redovniković, Ivana; Gaurina Srček, Višnja; Radošević, Kristina
Ready-to-use green polyphenolic extracts from food by-products // Food chemistry, 283 (2019), 628-636 doi:10.1016/j.foodchem.2019.01.061 (međunarodna recenzija, članak, znanstveni)


Naslov
Ready-to-use green polyphenolic extracts from food by-products

Autori
Panić, Manuela ; Radić Stojković, Marijana ; Kraljić, Klara ; Škevin, Dubravka ; Radojčić Redovniković, Ivana ; Gaurina Srček, Višnja ; Radošević, Kristina

Izvornik
Food chemistry (0308-8146) 283 (2019); 628-636

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Biological activities ; grape pomace ; natural deep eutectic solvents ; olive pomace ; polyphenolic compounds

Sažetak
To establish environmentally friendly polyphenolic extracts from grape and olive pomace, natural deep eutectic solvents (NADES) were used coupled with alternative energy sources – ultrasound and microwave irradiation. Obtained extracts were characterized by HPLC analysis, while antioxidant capacity was determined by ORAC method. Furthermore, in vitro cytotoxicity of prepared extracts was assessed by antiproliferation assay on two tumour cell lines, whereas for investigation of type of cell death or cell cycle arrest a flow cytometric analysis was applied. In addition, a detection of compounds with DNA/RNA-binding affinity in extracts was investigated by UV/Vis and circular dichroism spectroscopy. Grape pomace extract in NADES showed to be the best of all extracts tested, with regard to extraction of total polyphenolic compounds (p<0.05) and related biological activities such as antioxidant and antiproliferative activity. Prepared polyphenolic extracts in NADES could be considered as ready-to-use in food and pharmaceutical industry without demanding and expensive downstream purification steps.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija



POVEZANOST RADA


Projekt / tema
HRZZ-IP-2014-09-9550 - Zelena otapala za zelene tehnologije (Ivana Radojčić Redovniković, )
HRZZ-IP-2018-01-4694 - Molekularno prepoznavanje DNA:RNA hibridnih i višelančanih struktura u bioanalitičkim i in vitro sustavima (Marijana Radić Stojković, )

Ustanove
Prehrambeno-biotehnološki fakultet, Zagreb,
Institut "Ruđer Bošković", Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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