Hypoglycemia and Glucagon Utilization in Insulin- Treated Diabetic Patients (CROSBI ID 258448)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Vilović, Marino ; Tičinović Kurir, Tina ; Novak, Anela ; Krnić, Mladen ; Borovac, Josip Anđelo ; Lizatović, Ivan-Krešimir ; Kokić, Višnja ; Božić, Joško
engleski
Hypoglycemia and Glucagon Utilization in Insulin- Treated Diabetic Patients
Background: First choice of therapy for severe hypoglycemia outside hospital environment is glucagon injection, an undertaught and underused remedy. Aim of this study was to investigate knowledge about glucagon therapy, possession rate and usage rate in insulin- treated diabetic patients, with special emphasis on history of hypoglycemia and severe hypoglycemia episodes. Methods: In this cross- sectional study, 300 insulin-treated diabetic patients (146 males and 154 females, mean age 61.1±16.4 years) were recruited from comprehensive Diabetes Center in Croatia. Specialized self-administered, 13-item questionnaire regarding glucagon therapy and history of hypoglycemia was obtained from each patient, as well as data collected from medical history documentation. Results: Experience of hypoglycemic episode was reported by 233 (77.7%), and severe hypoglycemia by 73 (24.3%) patients. Participants with experience of hypoglycemia have significantly longer diabetes duration (17.2±11.2 vs. 11.9±8.5 years, P<0.001) and lower BMI values (26.38±3.97 vs. 31.11±7.17 kg/m2, P<0.001). Knowledge about glucagon therapy had 55.3% patients, 44.7% obtained it from the pharmacy, while glucagon was used in 35.6% cases of severe hypoglycemia. Glucagon knowledge was better in patients that attended at least one diabetes lecture (P=0.038), while educational level showed no statistical significance (P=0.286). Main significant positive predictor of glucagon knowledge was history of severe hypoglycemia (OR 4.71, 95% CI 1.38 – 16.02, P=0.013). Conclusions: Glucagon therapy was underused in treating severe hypoglycemia. It is highly important to emphasize value of quality education as one of the fundamentals of good diabetes management.
hypoglycemia treatment ; education ; diabetes mellitus
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Podaci o izdanju
128 (08)
2020.
493-498
objavljeno
0947-7349
1439-3646
10.1055/a-0741-6763
Povezanost rada
Kliničke medicinske znanosti