engleski

PEComa of the ovary: a case report.

Objective. PEComas have been reported in a wide variety of intraabdominal, bone, soft tissue, and visceral sites, including uterus, heart and gastrointestinal tract. The primary site of the PEComa in the ovary we hold extremely rare and therefore of valuable for showing. Methods. Thirty years old patients underwent surgery due to ultrasound established solid tumor of the left ovary. The tumor was 8 cm in diameter and contains small foci of hemorrhage. Fresh frozen section was suspected of ovarian granulosa cell tumor. On paraffin sections, tumor is composed of solid cell aggregates distributed perivasculary. The cytoplasms were clear or lightly eosinophilic and nuclei were larger with coarse chromatin. It was observed 3 to 9 mitosis/50 HPF. Results. Tumor was CK7, CK MNF116, EMA, actin SMA, calretinin, CD31, CK20, LCA, chromogranin A, WT1 negative.S-100, vimentin, melan A, melanosma HMB45 were positive.CD99, synaptophisin and c-Kit showed weak punctate cytoplasmic positivity. Conclusion(s). Like the other rare tumors, PEComas can cause difficulties in the interpretation of fresh frozen section as well as to assess the clinical behavior of the neoplasm.

PEComa, ovary

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