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Pregled bibliografske jedinice broj: 975739

Assessing the lithium nutritional status by analyzing its cumulative distribution in the hair and whole blood


(Federal State Scientific Institution) Mimica, Ninoslav; Prejac, Juraj; Skalny, Andrey A.; Grabeklis, Andrei R.; Momčilović, Berislav
Assessing the lithium nutritional status by analyzing its cumulative distribution in the hair and whole blood // Trace elements and electrolytes, 36 (2019), 3; 113-119 doi:10.5414/TEX01551. (međunarodna recenzija, članak, znanstveni)


Naslov
Assessing the lithium nutritional status by analyzing its cumulative distribution in the hair and whole blood

Autori
Mimica, Ninoslav ; Prejac, Juraj ; Skalny, Andrey A. ; Grabeklis, Andrei R. ; Momčilović, Berislav

Kolaboracija
Federal State Scientific Institution

Izvornik
Trace elements and electrolytes (0946-2104) 36 (2019), 3; 113-119

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Lithium ; nutritional status ; hair ; whole blood ; safety limits

Sažetak
Objective: Lithium was recently proclaimed to be an essential trace element in human nutrition. The aim of tins study was to assess lithium nutritional status by analyzing lithium frequency distribution in the long-term biological indicator tissue of hair (H-Li) and in the short-term biological indicator tissue of whole blood (WB-Li). Materials and methods: Hair samples were analyzed in 1, 073 apparently healthy adult Croats (339 males and 734 females) and the whole-blood lithium was analyzed in a random subsample of them (91 males and 143 females). Samples were analyzed using ICP-MS at the Center for Biotic Medicine, Moscow, Russia. Results: There were no gender-dependent differences in the lithium-adequate linear reference range for H-Li and WB-Li where lithium was (µgxg-1) 0.014 — 0.100 and 3.40 — 5.65, respectively. Conclusion: Lithium concentrations below 0.014 µgxg-1 for H-Li and 3.40 µgxg-1 for WB- Li would indicate lithium deficiency. The estimated upper safety lithium limits for H-Li and WB-Li were set at 0.100 and 6.65 µgxg-1, respectively. These preliminary data, are Important for a long-term biomonitoring of low-level lithium supplementation.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove
Medicinski fakultet, Zagreb,
Klinika za psihijatriju Vrapče,
Klinički bolnički centar Zagreb,
Institut za istraživanje i razvoj održivih eko sustava,
Sveučilište u Zagrebu

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI


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