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Pregled bibliografske jedinice broj: 973940

Effects of Long-Term Multimodal Psychosocial Treatment on Antipsychotic-Induced Metabolic Changes in Patients With First Episode Psychosis.


Rojnić Kuzman, Martina; Bošnjak Kuharić, Dina; Kekin, Ivana; Makarić, Porin; Madžarac, Zoran; Koričančić Makar, Ana; Kudlek Mikulić, Suzan; Bajić, Žarko; Bistrović, Petra; Bonacin, Dora; Vogrinc, Željka
Effects of Long-Term Multimodal Psychosocial Treatment on Antipsychotic-Induced Metabolic Changes in Patients With First Episode Psychosis. // Frontiers in psychiatry, 9 (2018), 488-488 doi:10.3389/fpsyt.2018.00488 (međunarodna recenzija, članak, znanstveni)


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Naslov
Effects of Long-Term Multimodal Psychosocial Treatment on Antipsychotic-Induced Metabolic Changes in Patients With First Episode Psychosis.

Autori
Rojnić Kuzman, Martina ; Bošnjak Kuharić, Dina ; Kekin, Ivana ; Makarić, Porin ; Madžarac, Zoran ; Koričančić Makar, Ana ; Kudlek Mikulić, Suzan ; Bajić, Žarko ; Bistrović, Petra ; Bonacin, Dora ; Vogrinc, Željka

Izvornik
Frontiers in psychiatry (1664-0640) 9 (2018); 488-488

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
antipsychotics ; day hospital ; first episode psychosis ; Metabolic abnormalities ; psychosocial intervention ; schizophrenia ; weight gain

Sažetak
Background: Antipsychotic-induced weight gain and metabolic abnormalities are one of the major challenges in the treatment of psychosis, contributing to the morbidity, mortality and treatment non-adherence. Different approaches were used to counteract these side effects but showed only limited or short-term effects. This study aims to analyse the effects of a long-term multimodal treatment program for first episode psychosis on antipsychotic-induced metabolic changes. Methods: We enrolled 71 patients with first episode psychosis treated at the Zagreb University Hospital Centre from 2016 until 2018. Participants were assigned to one of the two groups: day hospital program vs. treatment as usual (TAU). Outcomes were: body weight, blood glucose, lipids and cholesterol, psychopathology and global level of functioning during the 18-months follow-up. Results: Although the TAU group gained more weight and had higher increase of blood glucose, while the day hospital group had a higher increase in total cholesterol at 18th month follow-up, after the adjustment for age, gender and baseline measures, the type of treatment was not significantly associated with any of the primary outcome measures. Patients' psychopathology measures significantly decreased and their functional level significantly increased at month 18th in both groups. Conclusion: While both types of treatment were effective in reducing psychopathology and restoring the patients' level of functioning, both were relatively ineffective in counteracting antipsychotic-induced metabolic abnormalities and antipsychotic-induced weight gain.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
HRZZ-UIP-2014-09-1245 - Biomarkeri u shizofreniji – integracija komplementarnih prisutupa u praćenju osoba s prvom psihotičnom epizodom (Martina Rojnic Kuzman, )

Ustanove
Medicinski fakultet, Zagreb,
Klinika za psihijatriju Vrapče,
Klinički bolnički centar Zagreb

Citiraj ovu publikaciju

Rojnić Kuzman, Martina; Bošnjak Kuharić, Dina; Kekin, Ivana; Makarić, Porin; Madžarac, Zoran; Koričančić Makar, Ana; Kudlek Mikulić, Suzan; Bajić, Žarko; Bistrović, Petra; Bonacin, Dora; Vogrinc, Željka
Effects of Long-Term Multimodal Psychosocial Treatment on Antipsychotic-Induced Metabolic Changes in Patients With First Episode Psychosis. // Frontiers in psychiatry, 9 (2018), 488-488 doi:10.3389/fpsyt.2018.00488 (međunarodna recenzija, članak, znanstveni)
Rojnić Kuzman, M., Bošnjak Kuharić, D., Kekin, I., Makarić, P., Madžarac, Z., Koričančić Makar, A., Kudlek Mikulić, S., Bajić, Ž., Bistrović, P., Bonacin, D. & Vogrinc, Ž. (2018) Effects of Long-Term Multimodal Psychosocial Treatment on Antipsychotic-Induced Metabolic Changes in Patients With First Episode Psychosis.. Frontiers in psychiatry, 9, 488-488 doi:10.3389/fpsyt.2018.00488.
@article{article, year = {2018}, pages = {488-488}, DOI = {10.3389/fpsyt.2018.00488}, keywords = {antipsychotics, day hospital, first episode psychosis, Metabolic abnormalities, psychosocial intervention, schizophrenia, weight gain}, journal = {Frontiers in psychiatry}, doi = {10.3389/fpsyt.2018.00488}, volume = {9}, issn = {1664-0640}, title = {Effects of Long-Term Multimodal Psychosocial Treatment on Antipsychotic-Induced Metabolic Changes in Patients With First Episode Psychosis.}, keyword = {antipsychotics, day hospital, first episode psychosis, Metabolic abnormalities, psychosocial intervention, schizophrenia, weight gain} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


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