Genome rearrangements in radiation-resistant bacteria (CROSBI ID 670627)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa
Podaci o odgovornosti
Repar, Jelena ; Supek, Fran ; Klanjscek, Tin ; Warnecke, Tobias ; Zahradka, Ksenija ; Zahradka, Davor
engleski
Genome rearrangements in radiation-resistant bacteria
A number of bacterial, archaeal, and eukaryotic species are known for their resistance to ionizing radiation. One of the challenges these species face is a potent environmental source of DNA double-strand breaks, potential drivers of genome structure evolution. Efficient and accurate DNA double-strand break repair systems have been demonstrated in several unrelated radiation- resistant species and are putative adaptations to the DNA damaging environment. Such adaptations are expected to compensate for the genome- destabilizing effect of environmental DNA damage and may be expected to result in a more conserved gene order in radiation-resistant species. However, we show that rates of genome rearrangements, measured as loss of gene order conservation with time, are higher in radiation- resistant species in multiple, phylogenetically independent groups of bacteria. Furthermore, we explore whether detected high rearrangement rates in radiation-resistant species constitute a survival strategy or are a passive consequence of environmental DNA damage.
genome rearrangments ; gene order ; radiation-resistant species ; DNA double-strand breaks
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o prilogu
24-24.
2018.
objavljeno
Podaci o matičnoj publikaciji
Šarčević, Hrvoje ; Ugarković, Đurđica ; Vujaklija, Dušica ; Svetec, Ivan Krešimir ; Svetec Miklenić, Marina
Zagreb: Hrvatsko genetičko društvo
978-953-57128-1-7
Podaci o skupu
4th Congress of Croatian Geneticists with international participation
predavanje
26.09.2018-29.09.2018
Krk, Hrvatska