Salivary Morning Cortisol and Sleep Quality in Healthy Subjects (CROSBI ID 670428)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Knezović Zlatarić, Dubravka ; Alajbeg, Iva ; Roglić, Dunja ; Alajbeg, Ivan ; Illeš, Davor ; Vuletić, Lea ; Andabak Rogulj, Ana ; Lapić, Ivana ; Badel, Tomislav
engleski
Salivary Morning Cortisol and Sleep Quality in Healthy Subjects
Objectives: The aim of this study was to determine the normal inter- day variations of salivary awakening cortisol in healthy adult individuals and to explore its relationship with sleep quality as measured by Sleep cycle alarm clock. Methods: Sleep quality Fifteen adult subjects, 9 females and 6 males, (mean age 38.73±5.18 years), with no previously diagnosed sleep disorders, were included in the study. Subjects were asked to download the free version of the app Sleep cycle alarm clock (Northcube AB 8 Göteborg, Sweden) onto their iPhones through the App Store. All subjects were required to use the app for a minimum of 5 nights at home before participating in the study. After they had used the app for a minimum of 5 nights, subjects used the app for three consecutive nights. Sleep quality < 81% was considered as poor sleep quality . Morning Salivary Awakening Cortisol Assessment Five millilitres of whole unstimulated saliva was collected into a graduated tube (50 ml, self- standing centrifuge tubes, Ratiolab, Germany).Subjects were asked to collect saliva immediately after waking up during three consecutive days. Saliva aliquots, (1 ml), were stored at −80°C until analysed. Saliva samples were thawed and centrifuged prior to analysis (1000xg, 5 min). Salivary free cortisol levels were determined using a competitive ELISA kit (Demeditec Diagnostics GmbH, Germany). Results: Intra-individual variability for morning cortisol was 15- 42%. Objective poor sleepers (sleep quality < 81%) had significantly lower salivary awakening cortisol than good sleepers. Conclusions: Our study shows that the poor sleep quality, measured by Sleep cycle alarm clock for iPhones was associated with decreased salivary awakening cortisol.
salivary awakening cortisol ; healthy adults
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Podaci o prilogu
2955-2955.
2017.
objavljeno
Podaci o matičnoj publikaciji
Journal of Dental Research
Giannobile, William V
International Association for Dental Research
Podaci o skupu
IADR/AADR/CADR General Session
poster
20.03.2017-25.03.2017
San Francisco (CA), Sjedinjene Američke Države
Povezanost rada
Dentalna medicina, Temeljne medicinske znanosti