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Pregled bibliografske jedinice broj: 972198

Amino-β-lactams in Ugi reaction: An efficient method for preparation of functionalized peptidomimetics


Vazdar, Katarina; Jerić Ivanka
Amino-β-lactams in Ugi reaction: An efficient method for preparation of functionalized peptidomimetics // Tetrahedron, 74 (2018), 52; 7495-7506 doi:10.1016/j.tet.2018.11.028 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 972198 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Amino-β-lactams in Ugi reaction: An efficient method for preparation of functionalized peptidomimetics

Autori
Vazdar, Katarina ; Jerić Ivanka

Izvornik
Tetrahedron (0040-4020) 74 (2018), 52; 7495-7506

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Ugi reaction ; Amino-β-lactams ; Peptidomimetics

Sažetak
A synthetic strategy for the Ugi reaction on amino-β-lactam synthon 1 was developed. The Ugi reaction products 5 were obtained in satisfactory yields (47–78%) and generally, low diastereoselectivity (up to 72:28 dr). In case of Ugi products 5 derived from cyclohexylcarbaldehyde and amino-β-lactam 1, the reaction yields were lower (38–61%) but the products were obtained in high diastereoselectivity (>95:5).

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekti:
HRZZ-IP-2014-09-3102 - Višekomponentne reakcije u sintezi peptidnih mimetika (MIMICRy) (Jerić, Ivanka, HRZZ - 2014-09) ( POIROT)

Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Katarina Vazdar (autor)

Avatar Url Ivanka Jerić (autor)

Citiraj ovu publikaciju

Vazdar, Katarina; Jerić Ivanka
Amino-β-lactams in Ugi reaction: An efficient method for preparation of functionalized peptidomimetics // Tetrahedron, 74 (2018), 52; 7495-7506 doi:10.1016/j.tet.2018.11.028 (međunarodna recenzija, članak, znanstveni)
Vazdar, K. & Jerić Ivanka (2018) Amino-β-lactams in Ugi reaction: An efficient method for preparation of functionalized peptidomimetics. Tetrahedron, 74 (52), 7495-7506 doi:10.1016/j.tet.2018.11.028.
@article{article, author = {Vazdar, K. and Jeri\'{c} Ivanka}, year = {2018}, pages = {7495-7506}, DOI = {10.1016/j.tet.2018.11.028}, keywords = {Ugi reaction, Amino-β-lactams, Peptidomimetics}, journal = {Tetrahedron}, doi = {10.1016/j.tet.2018.11.028}, volume = {74}, number = {52}, issn = {0040-4020}, title = {Amino-β-lactams in Ugi reaction: An efficient method for preparation of functionalized peptidomimetics}, keyword = {Ugi reaction, Amino-β-lactams, Peptidomimetics} }
@article{article, author = {Vazdar, K. and Jeri\'{c} Ivanka}, year = {2018}, pages = {7495-7506}, DOI = {10.1016/j.tet.2018.11.028}, keywords = {Ugi reaction, Amino-β-lactams, Peptidomimetics}, journal = {Tetrahedron}, doi = {10.1016/j.tet.2018.11.028}, volume = {74}, number = {52}, issn = {0040-4020}, title = {Amino-β-lactams in Ugi reaction: An efficient method for preparation of functionalized peptidomimetics}, keyword = {Ugi reaction, Amino-β-lactams, Peptidomimetics} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • Arts & Humanities Citation Index (A&HCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


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